Literature DB >> 29946526

Implementation of an active, clinic-based child tuberculosis contact management strategy in western Kenya.

D Szkwarko1,2,3, P Owiti3,4, N Buziba5, C Bigelow6, C B Eaton2,7, E J Carter3,8.   

Abstract

Tuberculosis (TB) is a leading cause of childhood mortality. Isoniazid preventive therapy significantly reduces progression to TB disease. The World Health Organization recommends that high TB burden countries conduct child contact management (CCM) to identify exposed child contacts aged <5 years for screening and appropriate treatment. An active, clinic-based CCM strategy incorporating transport/screening reimbursement, monitoring and evaluation tools, and health care worker education was implemented in western Kenya. Among 169 identified child contacts aged <5 years, 146 (86%) underwent successful screening, of whom 43 (29%) were diagnosed with active TB. We describe our CCM strategy and its potential for enhancing screening and treatment efforts.

Entities:  

Keywords:  child contact management; isoniazid preventive therapy; pediatric TB

Year:  2018        PMID: 29946526      PMCID: PMC6012959          DOI: 10.5588/pha.17.0119

Source DB:  PubMed          Journal:  Public Health Action        ISSN: 2220-8372


  5 in total

1.  Implementing a tuberculosis child contact register to quantify children at risk for tuberculosis and HIV in Eldoret, Kenya.

Authors:  D Szkwarko; F Ogaro; P Owiti; E J Carter
Journal:  Public Health Action       Date:  2013-09-21

2.  Global Burden of Childhood Tuberculosis.

Authors:  Helen E Jenkins
Journal:  Pneumonia (Nathan)       Date:  2016-11-24

3.  Efficacy of isoniazid prophylactic therapy in prevention of tuberculosis in children: a meta-analysis.

Authors:  James Ayieko; Lisa Abuogi; Brett Simchowitz; Elizabeth A Bukusi; Allan H Smith; Arthur Reingold
Journal:  BMC Infect Dis       Date:  2014-02-20       Impact factor: 3.090

Review 4.  Child contact management in high tuberculosis burden countries: A mixed-methods systematic review.

Authors:  Daria Szkwarko; Yael Hirsch-Moverman; Lienki Du Plessis; Karen Du Preez; Catherine Carr; Anna M Mandalakas
Journal:  PLoS One       Date:  2017-08-01       Impact factor: 3.240

5.  The PREVENT study to evaluate the effectiveness and acceptability of a community-based intervention to prevent childhood tuberculosis in Lesotho: study protocol for a cluster randomized controlled trial.

Authors:  Yael Hirsch-Moverman; Andrea A Howard; Koen Frederix; Limakatso Lebelo; Anneke Hesseling; Sharon Nachman; Joanne E Mantell; Tsepang Lekhela; Llang Bridget Maama; Wafaa M El-Sadr
Journal:  Trials       Date:  2017-11-21       Impact factor: 2.279

  5 in total
  5 in total

1.  Tuberculosis: An Epidemic Perpetuated by Health Inequalities.

Authors:  Daria Szkwarko; Tara C Bouton; Natasha R Rybak; E Jane Carter; Silvia S Chiang
Journal:  R I Med J (2013)       Date:  2019-09-03

2.  One size does not fit all: preventing tuberculosis among child contacts.

Authors:  Daria Szkwarko; Yael Hirsch-Moverman
Journal:  BMJ Glob Health       Date:  2019-12-29

3.  Closing the loop in child TB contact management: completion of TB preventive therapy outcomes in western Kenya.

Authors:  James A Amisi; E Jane Carter; Enos Masini; Daria Szkwarko
Journal:  BMJ Open       Date:  2021-02-23       Impact factor: 2.692

4.  Screening tests for active pulmonary tuberculosis in children.

Authors:  Bryan Vonasek; Tara Ness; Yemisi Takwoingi; Alexander W Kay; Susanna S van Wyk; Lara Ouellette; Ben J Marais; Karen R Steingart; Anna M Mandalakas
Journal:  Cochrane Database Syst Rev       Date:  2021-06-28

5.  Distinct Risk Factors for Clinical and Bacteriologically Confirmed Tuberculosis among Child Household Contacts in a High-Burden Setting.

Authors:  Micaela Sandoval; Padma Swamy; Alexander W Kay; Pilar Ustero Alonso; Gloria Sisi Dube; Hypertia Hlophe-Dlamini; Anna M Mandalakas
Journal:  Am J Trop Med Hyg       Date:  2020-09-24       Impact factor: 3.707

  5 in total

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