Literature DB >> 29944194

A Method for Parasagittal Sectioning for Neuroanatomical Quantification of Brain Structures in the Adult Mouse.

Stephan C Collins1,2,3,4,5, Christel Wagner1,2,3,4, Léo Gagliardi1,2,3,4, Perrine F Kretz1,2,3,4, Marie-Christine Fischer1,2,3,4, Pascal Kessler1,2,3,4, Meghna Kannan1,2,3,4, Binnaz Yalcin1,2,3,4.   

Abstract

In this article, we present a standardized protocol for fast and robust neuroanatomical phenotyping of the adult mouse brain, which complements a previously published article (doi: 10.1002/cpmo.12) in Current Protocols in Mouse Biology. It is aimed at providing an experimental pipeline within an academic research setting from experimental work to data analysis. Our analysis focuses on one single parasagittal plane, covering the majority of brain regions involved in higher order cognitions such as the cortex, hippocampus, and cerebellum, for a total of 166 parameters of area, length, and cell-level measurements in contrast to 78 parameters in our previously published coronal screen. Benefits of using parasagittal analysis for large-scale neuroanatomic screens are discussed.
© 2018 by John Wiley & Sons, Inc. © 2018 John Wiley & Sons, Inc.

Entities:  

Keywords:  brain morphogenesis; histology; mouse phenotyping; parasagittal sectioning; ultra-standardized procedure

Mesh：

Year:  2018        PMID： 29944194     DOI： 10.1002/cpmo.48

Source DB:  PubMed          Journal:  Curr Protoc Mouse Biol        ISSN： 2161-2617


  9 in total

1.  Haploinsufficiency of the HIRA gene located in the 22q11 deletion syndrome region is associated with abnormal neurodevelopment and impaired dendritic outgrowth.

Authors:  Marie-Laure Vuillaume; Dévina C Ung; Valerie E Vancollie; Tjitske Kleefstra; Binnaz Yalcin; Frédéric Laumonnier; Annick Toutain; Médéric Jeanne; Christel Wagner; Stephan C Collins; Sandrine Vonwill; Damien Haye; Nora Chelloug; Rolph Pfundt; Joost Kummeling; Marie-Pierre Moizard; Sylviane Marouillat
Journal:  Hum Genet       Date:  2021-01-08       Impact factor: 4.132

2.  Conditional switching of KIF2A mutation provides new insights into cortical malformation pathogeny.

Authors:  Johan G Gilet; Ekaterina L Ivanova; Daria Trofimova; Gabrielle Rudolf; Hamid Meziane; Loic Broix; Nathalie Drouot; Jeremie Courraud; Valerie Skory; Paul Voulleminot; Maria Osipenko; Nadia Bahi-Buisson; Binnaz Yalcin; Marie-Christine Birling; Maria-Victoria Hinckelmann; Benjamin H Kwok; John S Allingham; Jamel Chelly
Journal:  Hum Mol Genet       Date:  2020-03-27       Impact factor: 6.150

3.  The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth.

Authors:  Sandra Schrötter; Christopher J Yuskaitis; Michael R MacArthur; Sarah J Mitchell; Aaron M Hosios; Maria Osipovich; Margaret E Torrence; James R Mitchell; Gerta Hoxhaj; Mustafa Sahin; Brendan D Manning
Journal:  Cell Rep       Date:  2022-05-17       Impact factor: 9.995

4.  Novel role of the synaptic scaffold protein Dlgap4 in ventricular surface integrity and neuronal migration during cortical development.

Authors:  Delfina M Romero; Karine Poirier; Richard Belvindrah; Imane Moutkine; Anne Houllier; Anne-Gaëlle LeMoing; Florence Petit; Anne Boland; Stephan C Collins; Mariano Soiza-Reilly; Binnaz Yalcin; Jamel Chelly; Jean-François Deleuze; Nadia Bahi-Buisson; Fiona Francis
Journal:  Nat Commun       Date:  2022-05-18       Impact factor: 17.694

5.  TUBG1 missense variants underlying cortical malformations disrupt neuronal locomotion and microtubule dynamics but not neurogenesis.

Authors:  Ekaterina L Ivanova; Johan G Gilet; Vadym Sulimenko; Arnaud Duchon; Gabrielle Rudolf; Karen Runge; Stephan C Collins; Laure Asselin; Loic Broix; Nathalie Drouot; Peggy Tilly; Patrick Nusbaum; Alexandre Vincent; William Magnant; Valerie Skory; Marie-Christine Birling; Guillaume Pavlovic; Juliette D Godin; Binnaz Yalcin; Yann Hérault; Pavel Dráber; Jamel Chelly; Maria-Victoria Hinckelmann
Journal:  Nat Commun       Date:  2019-05-13       Impact factor: 14.919

6.  A Positively Selected MAGEE2 LoF Allele Is Associated with Sexual Dimorphism in Human Brain Size and Shows Similar Phenotypes in Magee2 Null Mice.

Authors:  Michał Szpak; Stephan C Collins; Yan Li; Xiao Liu; Qasim Ayub; Marie-Christine Fischer; Valerie E Vancollie; Christopher J Lelliott; Yali Xue; Binnaz Yalcin; Huanming Yang; Chris Tyler-Smith
Journal:  Mol Biol Evol       Date:  2021-12-09       Impact factor: 16.240

7.  A knock-in mouse model for KCNQ2-related epileptic encephalopathy displays spontaneous generalized seizures and cognitive impairment.

Authors:  Mathieu Milh; Pierre Roubertoux; Najoua Biba; Julie Chavany; Adeline Spiga Ghata; Camille Fulachier; Stephan Christopher Collins; Christel Wagner; Jean-Christophe Roux; Binnaz Yalcin; Marie-Solenne Félix; Florence Molinari; Pierre-Pascal Lenck-Santini; Laurent Villard
Journal:  Epilepsia       Date:  2020-04-02       Impact factor: 5.864

8.  Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis.

Authors:  Stephan C Collins; Anna Mikhaleva; Katarina Vrcelj; Valerie E Vancollie; Christel Wagner; Nestor Demeure; Helen Whitley; Meghna Kannan; Rebecca Balz; Lauren F E Anthony; Andrew Edwards; Hervé Moine; Jacqueline K White; David J Adams; Alexandre Reymond; Christopher J Lelliott; Caleb Webber; Binnaz Yalcin
Journal:  Nat Commun       Date:  2019-08-01       Impact factor: 14.919

9.  Isolation and functional characterization of primary endothelial cells from mouse cerebral cortex.

Authors:  Julie Ouellette; Baptiste Lacoste
Journal:  STAR Protoc       Date:  2021-12-11
  9 in total

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