Ovarian endometrioid carcinoma with yolk sac tumor component in a postmenopausal woman.

Yolk sac tumor (YST) coexisting with a variety of histologic patterns have been described, but with an epithelial malignant component is extremely rare. It has been suggested that this rare tumor represents an adenocarcinoma with aberrant differentiation because it occurs in the same age range as epithelial ovarian carcinoma and shows an aggressive behavior and poor prognosis. Although chemotherapy is effective for pure YST, YST with endometrioid adenocarcinoma does not respond to chemotherapy. Here the authors report a postmenopousal women with ovarian endometrioid adenocarcinoma (OEC) associated with YST.