Literature DB >> 29942425

Efficacy and Tolerability of an Acne Treatment Regimen with Antiaging Benefits in Adult Women: A Pilot Study.

Lily I Jiang1,2,3,4, Peter D Hino1,2,3,4, Lydia Parker1,2,3,4, Thomas J Stephens1,2,3,4, John Mccook1,2,3,4, Vincent Gotz1,2,3,4.   

Abstract

Objective: The objective of this study was to assess clinical safety and efficacy of a novel acne treatment regimen in adult women.
Methods: Participants in the study included an ethnically diverse group of adult women (n=24) with mild-to-moderate acne who were treated twice daily with a topical regimen (cleanser, acne cream, and rebalancing gel) for eight weeks. Following baseline assessments, subjects returned to clinic at Weeks 2, 4, and 8 for clinical assessments and self-assessment questionnaires.
Results: Twenty-one of the 24 enrolled women completed the eight-week clinical trial. Statistically significant clinical improvements were seen in both acne and aging parameters over time. The product regimen was well tolerated without adverse reactions commonly seen with topical acne products.
Conclusion: The regimen demonstrated efficacy and tolerability in adult women with acne and signs of skin aging.

Entities:  

Keywords:  Adult female acne; acne treatment; liposomal sodium copper chlorophyllin complex; salicylic acid

Year:  2018        PMID: 29942425      PMCID: PMC6011872     

Source DB:  PubMed          Journal:  J Clin Aesthet Dermatol        ISSN: 1941-2789


  24 in total

1.  The quality of life in acne: a comparison with general medical conditions using generic questionnaires.

Authors:  E Mallon; J N Newton; A Klassen; S L Stewart-Brown; T J Ryan; A Y Finlay
Journal:  Br J Dermatol       Date:  1999-04       Impact factor: 9.302

Review 2.  Acne in adolescents: quality of life, self-esteem, mood, and psychological disorders.

Authors:  Lauren K Dunn; Jenna L O'Neill; Steven R Feldman
Journal:  Dermatol Online J       Date:  2011-01-15

3.  An acne grading method using photographic standards.

Authors:  C H Cook; R L Centner; S E Michaels
Journal:  Arch Dermatol       Date:  1979-05

Review 4.  Overview of acne and its treatment.

Authors:  Diane M Thiboutot
Journal:  Cutis       Date:  2008-01

5.  The prevalence of acne vulgaris in adolescence.

Authors:  J L Burton; W J Cunliffe; I Stafford; S Shuster
Journal:  Br J Dermatol       Date:  1971-08       Impact factor: 9.302

6.  Topical Treatment With Liposomal Sodium Copper Chlorophyllin Complex in Subjects With Facial Redness and Erythematotelangiectatic Rosacea: Case Studies.

Authors:  David B Vasily
Journal:  J Drugs Dermatol       Date:  2015-10       Impact factor: 2.114

7.  Pilot Study of Topical Copper Chlorophyllin Complex in Subjects With Facial Acne and Large Pores.

Authors:  Thomas J Stephens; John P McCook; James H Herndon
Journal:  J Drugs Dermatol       Date:  2015-06       Impact factor: 2.114

Review 8.  Persistent acne in women : implications for the patient and for therapy.

Authors:  Christina Williams; Alison M Layton
Journal:  Am J Clin Dermatol       Date:  2006       Impact factor: 7.403

9.  Top dermatologic diagnoses by age.

Authors:  Erin T Landis; Scott A Davis; Arash Taheri; Steven R Feldman
Journal:  Dermatol Online J       Date:  2014-04-16

10.  Ability of sodium copper chlorophyllin complex to repair photoaged skin by stimulation of biomarkers in human extracellular matrix.

Authors:  John P McCook; Thomas J Stephens; Lily I Jiang; Robert M Law; Vincent Gotz
Journal:  Clin Cosmet Investig Dermatol       Date:  2016-07-25
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  1 in total

1.  Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays.

Authors:  Lilian Mussi; André Rolim Baby; Flavio Bueno Camargo Junior; Giovana Padovani; Bianca da Silva Sufi; Wagner Vidal Magalhães
Journal:  Molecules       Date:  2021-11-05       Impact factor: 4.411

  1 in total

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