Literature DB >> 2994146

Behavioural similarities between mother rats and benzodiazepine-treated non-maternal animals.

S Hansen, A Ferreira, M E Selart.   

Abstract

Mother rats nursing large litters are hyperphagic, aggressive towards conspecifics, and show less freezing behaviour than non-maternal animals. These naturally occurring adaptations resemble those elicited by benzodiazepine treatment in virgin rats, indicating a common neurochemical change in the brains of mother rats and benzodiazepine-treated virgins. In line with this hypothesis, it was found that three functional benzodiazepine antagonists (FG 7142, pentylenetetrazol, caffeine) decreased food intake, lowered aggression and strengthened freezing in lactating mother rats. These psychopharmacological observations support the idea that GABA neurotransmission is enhanced during motherhood in the rat.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 2994146     DOI： 10.1007/bf00432226

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  25 in total

Review 1.  The effects of benzodiazepines on aggression: reduced or increased?

Authors:  A DiMascio
Journal:  Psychopharmacologia       Date:  1973-05-21

2.  Intraspecies aggression in rats: effects of d-amphetamine and chlordiazepoxide.

Authors:  K A Miczek
Journal:  Psychopharmacologia       Date:  1974

3.  Postpartum aggression in rats: II. Dependence on maternal sensitivity to young and effects of experience with pregnancy and parturition.

Authors:  M S Erskine; R J Barfield; B D Goldman
Journal:  J Comp Physiol Psychol       Date:  1980-06

4.  Influence of castration and brain GABA levels in three strains of mice on aggression towards lactating intruders.

Authors:  M Haug; S Simler; L Ciesielski; P Mandel; R Moutier
Journal:  Physiol Behav       Date:  1984-05

5.  The action of stress, beta-carbolines, diazepam, and Ro 15-1788 on GABA receptors in the rat brain.

Authors:  G Biggio
Journal:  Adv Biochem Psychopharmacol       Date:  1983

6.  Behavioural effects of pentylenetetrazole reversed by chlordiazepoxide and enhanced by RO 15-1788.

Authors:  S E File
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1984-06       Impact factor: 3.000

Review 7.  The neuropharmacology of various diazepam antagonists.

Authors:  C A Boast; P S Bernard; B S Barbaz; K M Bergen
Journal:  Neuropharmacology       Date:  1983-12       Impact factor: 5.250

8.  Postpartum aggression in rats: I. Effects of hypophysectomy.

Authors:  M S Erskine; R J Barfield; B D Goldman
Journal:  J Comp Physiol Psychol       Date:  1980-06

9.  Ro 15-1788 and beta-CCE selectively eliminate diazepam-induced feeding in the rabbit.

Authors:  R S Mansbach; J A Stanley; J E Barrett
Journal:  Pharmacol Biochem Behav       Date:  1984-05       Impact factor: 3.533

10.  Isolation, characterization, and purification to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors.

Authors:  A Guidotti; C M Forchetti; M G Corda; D Konkel; C D Bennett; E Costa
Journal:  Proc Natl Acad Sci U S A       Date:  1983-06       Impact factor: 11.205
View more
  15 in total

1.  Limited changes of mouse maternal care after prenatal oxazepam: dissociation from pup-related stimulus perception.

Authors:  S Petruzzi; F Chiarotti; E Alleva; G Laviola
Journal:  Psychopharmacology (Berl)       Date:  1995-11       Impact factor: 4.530

2.  The effect of the beta-carboline FG 7142 on the behaviour of male rats in a living cage: an ethological analysis of social and nonsocial behaviour.

Authors:  C H Beck; S J Cooper
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

3.  Altered gene expression in mice selected for high maternal aggression.

Authors:  S C Gammie; A P Auger; H M Jessen; R J Vanzo; T A Awad; S A Stevenson
Journal:  Genes Brain Behav       Date:  2006-08-29       Impact factor: 3.449

Review 4.  Anxiogenic properties of beta-CCE and FG 7142: a review of promises and pitfalls.

Authors:  M H Thiébot; P Soubrié; D Sanger
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530

5.  Autoradiographic analysis of GABAA receptor binding in the neural anxiety network of postpartum and non-postpartum laboratory rats.

Authors:  Stephanie M Miller; Joseph S Lonstein
Journal:  Brain Res Bull       Date:  2011-06-01       Impact factor: 4.077

6.  Use of the light-dark box to compare the anxiety-related behavior of virgin and postpartum female rats.

Authors:  Stephanie M Miller; Christopher C Piasecki; Joseph S Lonstein
Journal:  Pharmacol Biochem Behav       Date:  2011-08-07       Impact factor: 3.533

7.  Maternal defense: breast feeding increases aggression by reducing stress.

Authors:  Jennifer Hahn-Holbrook; Julianne Holt-Lunstad; Colin Holbrook; Sarah M Coyne; E Thomas Lawson
Journal:  Psychol Sci       Date:  2011-08-26

8.  Associations among within-litter differences in early mothering received and later emotional behaviors, mothering, and cortical tryptophan hydroxylase-2 expression in female laboratory rats.

Authors:  Christina M Ragan; Kaitlyn M Harding; Joseph S Lonstein
Journal:  Horm Behav       Date:  2015-07-26       Impact factor: 3.587

9.  Beta--CCE and FG 7142 increase defensiveness during intraspecies encounters in mice.

Authors:  A Sulcová; M Krsiak; P Donát
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

10.  Oxytocin receptor distribution reflects social organization in monogamous and polygamous voles.

Authors:  T R Insel; L E Shapiro
Journal:  Proc Natl Acad Sci U S A       Date:  1992-07-01       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.