Literature DB >> 2994132

Transposition behavior of IS15 and its progenitor IS15-delta: are cointegrates exclusive end products?

P Trieu-Cuot, P Courvalin.   

Abstract

We report that the major product of IS15-promoted transposition is a cointegrate. When present in the multicopy plasmid pBR322, IS15 and its progenitor IS15-delta mediate the formation of cointegrates at frequencies of 3.5 X 10(-4) and 2.9 X 10(-5), respectively. We have studied the stability of the cointegrates generated by IS15 and IS15-delta. While these structures are resolved in a rec+ host, they were stable in a rec- host. These observations suggest that neither IS15 nor IS15-delta encode a resolvase and that cointegration is an end product of their transposition process. These properties of IS15-delta and IS15 can explain the transitions from IS15-delta to IS15 and from IS15 to IS15-delta observed in vivo.

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Year:  1985        PMID： 2994132     DOI： 10.1016/0147-619x(85)90034-4

Source DB:  PubMed          Journal:  Plasmid        ISSN： 0147-619X            Impact factor:   3.466


  13 in total

1.  Evolution of AbGRI2-0, the Progenitor of the AbGRI2 Resistance Island in Global Clone 2 of Acinetobacter baumannii.

Authors:  Grace A Blackwell; Steven J Nigro; Ruth M Hall
Journal:  Antimicrob Agents Chemother       Date:  2015-12-14       Impact factor: 5.191

2.  Acquisition by a Campylobacter-like strain of aphA-1, a kanamycin resistance determinant from members of the family Enterobacteriaceae.

Authors:  M Ouellette; G Gerbaud; T Lambert; P Courvalin
Journal:  Antimicrob Agents Chemother       Date:  1987-07       Impact factor: 5.191

3.  Site-specific transposition of insertion sequence IS630.

Authors:  T Tenzen; S Matsutani; E Ohtsubo
Journal:  J Bacteriol       Date:  1990-07       Impact factor: 3.490

4.  Characterization of transposon Tn1528, which confers amikacin resistance by synthesis of aminoglycoside 3'-O-phosphotransferase type VI.

Authors:  T Lambert; G Gerbaud; P Courvalin
Journal:  Antimicrob Agents Chemother       Date:  1994-04       Impact factor: 5.191

5.  A novel extended-spectrum TEM-type beta-lactamase (TEM-52) associated with decreased susceptibility to moxalactam in Klebsiella pneumoniae.

Authors:  C Poyart; P Mugnier; G Quesne; P Berche; P Trieu-Cuot
Journal:  Antimicrob Agents Chemother       Date:  1998-01       Impact factor: 5.191

6.  Worldwide disseminated armA aminoglycoside resistance methylase gene is borne by composite transposon Tn1548.

Authors:  M Galimand; S Sabtcheva; P Courvalin; T Lambert
Journal:  Antimicrob Agents Chemother       Date:  2005-07       Impact factor: 5.191

7.  Loss of intrinsic aminoglycoside resistance in Acinetobacter haemolyticus as a result of three distinct types of alterations in the aac(6')-Ig gene, including insertion of IS17.

Authors:  E Rudant; P Courvalin; T Lambert
Journal:  Antimicrob Agents Chemother       Date:  1997-12       Impact factor: 5.191

8.  CTX-M-5, a novel cefotaxime-hydrolyzing beta-lactamase from an outbreak of Salmonella typhimurium in Latvia.

Authors:  P A Bradford; Y Yang; D Sahm; I Grope; D Gardovska; G Storch
Journal:  Antimicrob Agents Chemother       Date:  1998-08       Impact factor: 5.191

9.  Conjugative plasmid transfer from Enterococcus faecalis to Escherichia coli.

Authors:  P Trieu-Cuot; C Carlier; P Courvalin
Journal:  J Bacteriol       Date:  1988-09       Impact factor: 3.490

10.  Insertion Sequence IS26 Reorganizes Plasmids in Clinically Isolated Multidrug-Resistant Bacteria by Replicative Transposition.

Authors:  Susu He; Alison Burgess Hickman; Alessandro M Varani; Patricia Siguier; Michael Chandler; John P Dekker; Fred Dyda
Journal:  MBio       Date:  2015-06-09       Impact factor: 7.867
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