Literature DB >> 29939910

Quality-adjusted Life Years (QALY) for 15 Chronic Conditions and Combinations of Conditions Among US Adults Aged 65 and Older.

Haomiao Jia1, Erica I Lubetkin2, John P Barile3, Willi Horner-Johnson4, Kimberly DeMichele5, Debra S Stark5, Matthew M Zack6, William W Thompson7.   

Abstract

BACKGROUND: Although the life expectancy for the US population has increased, a high proportion of this population has lived with ≥1 chronic conditions. We have quantified the burden of disease associated with 15 chronic conditions and combinations of conditions by estimating quality-adjusted life years (QALYs) for older US adults. RESEARCH
DESIGN: Data were from the Medicare Health Outcomes Survey Cohort 15 (baseline survey in 2012, follow-up survey 2014, with mortality follow-up through January 31, 2015). We included individuals aged 65 years and older (n=96,481). We estimated mean QALY throughout the remainder of the lifetime according to the occurrence of these conditions.
RESULTS: The age-adjusted QALY was 5.8 years for men and 7.8 years for women. Over 90% respondents reported at least 1 condition and 72% reported multiple conditions. Respondents with depression and congestive heart failure had the lowest age-adjusted QALY (1.1-1.5 y for men and 1.5-2.2 y for women), whereas those with hypertension, arthritis, and sciatica had higher QALY (4.2-5.4 and 6.4-7.2 y, respectively). Having either depression or congestive heart failure and any 1 or 2 of the other 13 conditions was associated with the lowest QALY among the possible dyads and triads of chronic conditions. Dyads and triads with hypertension or arthritis were more prevalent, but had higher QALY.
CONCLUSIONS: Understanding the burden of disease for common chronic conditions and for combinations of these conditions is useful for delivering high-quality primary care that could be tailored for individuals with combinations of chronic conditions.

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Year:  2018        PMID: 29939910     DOI: 10.1097/MLR.0000000000000943

Source DB:  PubMed          Journal:  Med Care        ISSN: 0025-7079            Impact factor:   2.983


  7 in total

1.  QALY losses for chronic diseases and its social distribution in the general population: results from the Belgian Health Interview Survey.

Authors:  Lisa Van Wilder; Brecht Devleesschauwer; Els Clays; Johan Van der Heyden; Rana Charafeddine; Aline Scohy; Delphine De Smedt
Journal:  BMC Public Health       Date:  2022-07-07       Impact factor: 4.135

2.  Optimal allocation of limited vaccine to control an infectious disease: Simple analytical conditions.

Authors:  Isabelle J Rao; Margaret L Brandeau
Journal:  Math Biosci       Date:  2021-04-26       Impact factor: 2.144

3.  Systematic review on the instruments used for measuring the association of the level of multimorbidity and clinically important outcomes.

Authors:  Eng Sing Lee; Hui Li Koh; Elaine Qiao-Ying Ho; Sok Huang Teo; Fang Yan Wong; Bridget L Ryan; Martin Fortin; Moira Stewart
Journal:  BMJ Open       Date:  2021-05-05       Impact factor: 2.692

4.  Life Expectancy Trends Among Integrated Health Care System Enrollees, 2014-2017.

Authors:  Anthony Finch; M Cabell Jonas; Kevin Rubenstein; Eric Watson; Sundeep Basra; Jose Martinez; Michael Horberg
Journal:  Perm J       Date:  2021-12-14

5.  Fexapotide triflutate vs oral pharmacotherapy as initial therapy for moderate-to-severe benign prostate hyperplasia patients: a cost-effectiveness analysis.

Authors:  Yifan Wei; Joel W Hay; Alan R Hay; Sze-Chuan Suen
Journal:  BMC Urol       Date:  2022-05-13       Impact factor: 2.090

6.  Exploratory Analysis of the Economically Justifiable Price of a Hypothetical RSV Vaccine for Older Adults in the Netherlands and the United Kingdom.

Authors:  F Zeevat; J Luttjeboer; J H J Paulissen; J van der Schans; P Beutels; C Boersma; M J Postma
Journal:  J Infect Dis       Date:  2022-08-12       Impact factor: 7.759

7.  The impact of multimorbidity patterns on health-related quality of life in the general population: results of the Belgian Health Interview Survey.

Authors:  Lisa Van Wilder; Brecht Devleesschauwer; Els Clays; Stefanie De Buyser; Johan Van der Heyden; Rana Charafeddine; Pauline Boeckxstaens; Dirk De Bacquer; Sophie Vandepitte; Delphine De Smedt
Journal:  Qual Life Res       Date:  2021-08-23       Impact factor: 4.147

  7 in total

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