Literature DB >> 29939018

Cancer Metabolism: Current Understanding and Therapies.

Jessica L Counihan1, Elizabeth A Grossman1, Daniel K Nomura1.   

Abstract

Dysregulation of cancer cell metabolism contributes to abnormal cell growth, the biological end point of cancer. We review here numerous affected oncogenes and metabolic pathways common in cancer and how they contribute to cancer pathogenesis and malignancy. This review also discusses various pharmacological manipulations that take advantage of these metabolic abnormalities and the current targeted therapies that have arisen from this research.

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Year:  2018        PMID： 29939018     DOI： 10.1021/acs.chemrev.7b00775

Source DB:  PubMed          Journal:  Chem Rev        ISSN： 0009-2665            Impact factor:   60.622


  32 in total

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Review 2.  Isotope tracing in health and disease.

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Review 3.  Enhancing CAR-T cell efficacy in solid tumors by targeting the tumor microenvironment.

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Review 4.  DHODH and cancer: promising prospects to be explored.

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Review 5.  Fundamentals to function: Quantitative and scalable approaches for measuring protein stability.

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6.  Protein Labeling and Crosslinking by Covalent Aptamers.

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Journal:  Angew Chem Int Ed Engl       Date:  2021-06-09       Impact factor: 16.823

Review 7.  Molecular targets and anticancer activity of quinoline-chalcone hybrids: literature review.

Authors:  Mamdouh F A Mohamed; Gamal El-Din A Abuo-Rahma
Journal:  RSC Adv       Date:  2020-08-21       Impact factor: 4.036

Review 8.  Metabolic Reprogramming of Colorectal Cancer Cells and the Microenvironment: Implication for Therapy.

Authors:  Miljana Nenkov; Yunxia Ma; Nikolaus Gaßler; Yuan Chen
Journal:  Int J Mol Sci       Date:  2021-06-10       Impact factor: 5.923

9.  MIR210HG regulates glycolysis, cell proliferation, and metastasis of pancreatic cancer cells through miR-125b-5p/HK2/PKM2 axis.

Authors:  Tianzhu Yu; Guoping Li; Chenggang Wang; Gaoquan Gong; Liangwen Wang; Changyu Li; Yi Chen; Xiaolin Wang
Journal:  RNA Biol       Date:  2021-06-10       Impact factor: 4.766

10.  Flavin dependency undermines proteome stability, lipid metabolism and cellular proliferation during vitamin B2 deficiency.

Authors:  Adrían Martínez-Limón; Giulia Calloni; Robert Ernst; R Martin Vabulas
Journal:  Cell Death Dis       Date:  2020-09-07       Impact factor: 8.469
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