Shimels Hussien Mohammed1, Hailu Taye2, Tesfamichael Awoke Sissay3, Bagher Larijani4, Ahmad Esmaillzadeh5,6,7. 1. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences-International Campus (TUMS-IC), Tehran, Iran. 2. Unit of Reproductive Health, Addis Ababa City Administration Health Bureau, Addis Ababa, Ethiopia. 3. Department of Public Health, Wollo University, Dessie, Ethiopia. 4. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. 5. Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. a-esmaillzadeh@tums.ac.ir. 6. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran. a-esmaillzadeh@tums.ac.ir. 7. Department of Community Nutrition, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. a-esmaillzadeh@tums.ac.ir.
Abstract
PURPOSE: Teff, an iron-rich staple grain in Ethiopia, is consumed mainly in the form of teff injera (TI). Studies on the association of TI consumption with anemia are limited. We aimed to determine the association of frequencies of TI consumption with anemia, in Addis Ababa, Ethiopia. METHODS: We conducted a hospital-based case-control study involving 592 pregnant women: 187 anemic cases, and 405 non-anemic controls. TI consumption was assessed by a food frequency questionnaire (FFQ). Multiple logistic regression, adjusted for dietary and non-dietary covariates, was performed to determine the relation of TI consumption to anemia status. RESULTS: We found that a decrease in frequency of TI consumption was significantly associated with an increase in the likelihood of anemia (p-trend = 0.009). Compared with everyday TI consumption, the adjusted odds ratios (AORs) of anemia associated with the other frequencies of teff consumption were 1.50 [95% confidence interval (CI) 0.71, 3.23; p = 0.285] for every other day, 2.13 (95% CI 1.03, 4.41; p = 0.04) for 1-2 times a week, and 3.17 (95% CI 1.62, 6.22; p < 0.001) for once in 2 weeks. CONCLUSIONS: Teff consumption was associated with reduced odds of anemia in pregnant women. Further studies are warranted, including determining the feasibility and effectiveness of TI use for anemia prevention. REGISTRATION: The study was registered as https://clinicaltrials.gov/ct2/show/NCT03251664 .
PURPOSE: Teff, an iron-rich staple grain in Ethiopia, is consumed mainly in the form of teff injera (TI). Studies on the association of TI consumption with anemia are limited. We aimed to determine the association of frequencies of TI consumption with anemia, in Addis Ababa, Ethiopia. METHODS: We conducted a hospital-based case-control study involving 592 pregnant women: 187 anemic cases, and 405 non-anemic controls. TI consumption was assessed by a food frequency questionnaire (FFQ). Multiple logistic regression, adjusted for dietary and non-dietary covariates, was performed to determine the relation of TI consumption to anemia status. RESULTS: We found that a decrease in frequency of TI consumption was significantly associated with an increase in the likelihood of anemia (p-trend = 0.009). Compared with everyday TI consumption, the adjusted odds ratios (AORs) of anemia associated with the other frequencies of teff consumption were 1.50 [95% confidence interval (CI) 0.71, 3.23; p = 0.285] for every other day, 2.13 (95% CI 1.03, 4.41; p = 0.04) for 1-2 times a week, and 3.17 (95% CI 1.62, 6.22; p < 0.001) for once in 2 weeks. CONCLUSIONS: Teff consumption was associated with reduced odds of anemia in pregnant women. Further studies are warranted, including determining the feasibility and effectiveness of TI use for anemia prevention. REGISTRATION: The study was registered as https://clinicaltrials.gov/ct2/show/NCT03251664 .
Entities:
Keywords:
Anemia; Eragrostis tef; Iron deficiency anemia; Teff
Authors: Yewelsew Abebe; Alemtsehay Bogale; K Michael Hambidge; Barbara J Stoecker; Isabel Arbide; Akilu Teshome; Nancy F Krebs; Jamie E Westcott; Karl B Bailey; Rosalind S Gibson Journal: Public Health Nutr Date: 2007-07-05 Impact factor: 4.022