Literature DB >> 29936248

U-BIOPRED: evaluation of the value of a public-private partnership to industry.

John H Riley1, Veit J Erpenbeck2, John G Matthews3, Cecile T J Holweg3, Christopher Compton4, Wolfgang Seibold5, Timothy Higenbottam6, Scott Wagers7, Anthony Rowe8, David Myles9.   

Abstract

Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes (U-BIOPRED) was initiated in the first year of the Innovative Medicines Initiative (IMI). It was an ambitious plan to tackle the understanding of asthma through an integration of clinical and multi-'omics approaches that necessitated the bringing together of industry, academic, and patient representatives because it was too large to be managed by any one of the partners in isolation. It was a novel experience for all concerned. In this review, we describe the main features of the U-BIOPRED experience from the industry perspective. We list some of the key advantages and learnings from the perspective of the authors, and also improvements that we feel could be made in future projects.
Copyright © 2018 Elsevier Ltd. All rights reserved.

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Year:  2018        PMID: 29936248     DOI: 10.1016/j.drudis.2018.06.015

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN: 1359-6446            Impact factor:   7.851


  3 in total

1.  Unmet Needs in Severe Asthma Subtyping and Precision Medicine Trials. Bridging Clinical and Patient Perspectives.

Authors:  Salman Siddiqui; Loren C Denlinger; Stephen J Fowler; Praveen Akuthota; Dominick E Shaw; Liam G Heaney; Louise Brown; Mario Castro; Tonya A Winders; Monica Kraft; Scott Wagers; Michael C Peters; Ian D Pavord; Samantha Walker; Nizar N Jarjour
Journal:  Am J Respir Crit Care Med       Date:  2019-04-01       Impact factor: 21.405

2.  Phenotypes of wheezing and asthma in preschool children.

Authors:  Christina G Kwong; Leonard B Bacharier
Journal:  Curr Opin Allergy Clin Immunol       Date:  2019-04

Review 3.  Crowdsourcing and open innovation in drug discovery: recent contributions and future directions.

Authors:  David C Thompson; Jörg Bentzien
Journal:  Drug Discov Today       Date:  2020-10-02       Impact factor: 7.851

  3 in total

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