Literature DB >> 29936247

Renovation as innovation: is repurposing the future of drug discovery research?

Arthur Neuberger1, Nektarios Oraiopoulos2, Donald L Drakeman3.   

Abstract

Mesh：

Year:  2018        PMID： 29936247     DOI： 10.1016/j.drudis.2018.06.012

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


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  13 in total

1.  The failure of drug repurposing for COVID-19 as an effect of excessive hypothesis testing and weak mechanistic evidence.

Authors:  Mariusz Maziarz; Adrian Stencel
Journal:  Hist Philos Life Sci       Date:  2022-10-18       Impact factor: 1.452

2.  Repurposing FDA approved drugs as possible anti-SARS-CoV-2 medications using ligand-based computational approaches: sum of ranking difference-based model selection.

Authors:  Priyanka De; Vinay Kumar; Supratik Kar; Kunal Roy; Jerzy Leszczynski
Journal:  Struct Chem       Date:  2022-06-07       Impact factor: 1.795

Review 3.  Current Status of COVID-19 Therapies and Drug Repositioning Applications.

Authors:  Ozlem Altay; Elyas Mohammadi; Simon Lam; Hasan Turkez; Jan Boren; Jens Nielsen; Mathias Uhlen; Adil Mardinoglu
Journal:  iScience       Date:  2020-06-20

4.  Prediction of Potential Drug-Disease Associations through Deep Integration of Diversity and Projections of Various Drug Features.

Authors:  Ping Xuan; Yingying Song; Tiangang Zhang; Lan Jia
Journal:  Int J Mol Sci       Date:  2019-08-22       Impact factor: 5.923

5.  Convolutional Neural Network and Bidirectional Long Short-Term Memory-Based Method for Predicting Drug-Disease Associations.

Authors:  Ping Xuan; Yilin Ye; Tiangang Zhang; Lianfeng Zhao; Chang Sun
Journal:  Cells       Date:  2019-07-11       Impact factor: 6.600

Review 6.  Drug repurposing for breast cancer therapy: Old weapon for new battle.

Authors:  Sadhna Aggarwal; Sumit Singh Verma; Sumit Aggarwal; Subash Chandra Gupta
Journal:  Semin Cancer Biol       Date:  2019-09-21       Impact factor: 15.707

7.  Using the drug repositioning approach to develop a novel therapy, tipepidine hibenzate sustained-release tablet (TS-141), for children and adolescents with attention-deficit/hyperactivity disorder.

Authors:  Takuya Saito; Yushiro Yamashita; Akemi Tomoda; Takashi Okada; Hideo Umeuchi; Saki Iwamori; Satoru Shinoda; Akiko Mizuno-Yasuhira; Hidetoshi Urano; Izumi Nishino; Kazuhiko Saito
Journal:  BMC Psychiatry       Date:  2020-11-10       Impact factor: 3.630

8.  Identification of Repurposable Drugs and Adverse Drug Reactions for Various Courses of COVID-19 Based on Single-Cell RNA Sequencing Data.

Authors:  Zhihan Wang; Kai Guo; Pan Gao; Qinqin Pu; Min Wu; Changlong Li; Junguk Hur
Journal:  ArXiv       Date:  2020-05-16

9.  Repurposable drugs for SARS-CoV-2 and influenza sepsis with scRNA-seq data targeting post-transcription modifications.

Authors:  Zhihan Wang; Kai Guo; Pan Gao; Qinqin Pu; Changlong Li; Junguk Hur; Min Wu
Journal:  Precis Clin Med       Date:  2021-08-28

10.  α-Asarone Attenuates Osteoclastogenesis and Prevents Against Oestrogen-Deficiency Induced Osteoporosis.

Authors:  Hao Tian; Tao Jiang; Kai Yang; Ruonan Ning; Tianqi Wang; Qi Zhou; Niandong Qian; Ping Huang; Lei Guo; Min Jiang; Xiaobing Xi; Xing Xu; Lianfu Deng
Journal:  Front Pharmacol       Date:  2022-03-18       Impact factor: 5.810
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