Stasia Rouse1, Matthew Wodziak2. 1. Department of Neurology, Loyola University, Maywood, IL, USA. 2. Department of Neurology, Loyola University, Maywood, IL, USA. Matthew.Wodziak@luhs.org.
Abstract
PURPOSE OF REVIEW: Hiccups are a common problem that crosses multiple disciplines including neurology, gastroenterology and pulmonology, and primary care. There are no formal guidelines to the treatment of intractable hiccups and treatment is based on experience and anecdotal evidence often relying on older medications. We have reviewed the relevant literature with an emphasis on the last five years or so in management of intractable hiccups. RECENT FINDINGS: The production of hiccups is a complex mechanism which involves multiple neurotransmitters and anatomical structure within the central and peripheral nervous system. A number of medications and other therapy have been reported successful for intractable hiccups. Intractable hiccups can occur more often than we realize and present to multiple medical disciplines. A number of pharmacologic option have been found to be useful including dopamine-blocking medication, baclofen, and gabapentin along with anticonvulsants.
PURPOSE OF REVIEW: Hiccups are a common problem that crosses multiple disciplines including neurology, gastroenterology and pulmonology, and primary care. There are no formal guidelines to the treatment of intractable hiccups and treatment is based on experience and anecdotal evidence often relying on older medications. We have reviewed the relevant literature with an emphasis on the last five years or so in management of intractable hiccups. RECENT FINDINGS: The production of hiccups is a complex mechanism which involves multiple neurotransmitters and anatomical structure within the central and peripheral nervous system. A number of medications and other therapy have been reported successful for intractable hiccups. Intractable hiccups can occur more often than we realize and present to multiple medical disciplines. A number of pharmacologic option have been found to be useful including dopamine-blocking medication, baclofen, and gabapentin along with anticonvulsants.
Authors: Sofía Portela-Sánchez; Antonio Sánchez-Soblechero; Pedro José Melgarejo Otalora; Ángela Rodríguez López; Gabriel Velilla Alonso; Michael Armando Palacios-Mendoza; Carlos Cátedra Caramé; Laura Amaya Pascasio; Miguel Mas Serrano; Andreu Massot-Tarrús; Beatriz De La Casa-Fages; Fernando Díaz-Otero; Irene Catalina; Jose Manuel García Domínguez; Javier Ricardo Pérez-Sánchez; José Luis Muñoz-Blanco; Francisco Grandas Journal: Eur J Neurol Date: 2021-02-03 Impact factor: 6.288