Literature DB >> 2993470

Growth factor-mediated tumor cell proliferation in hairy cell leukemia.

R J Ford, L Yoshimura, J Morgan, J Quesada, R Montagna, A Maizel.   

Abstract

Leukemic B cells from seven patients with hairy cell leukemia (HCL), six of which contained the Tac antigen, were assayed in vitro for growth factor-mediated cell proliferation. The HCL cells showed typical phenotypic profiles by monoclonal antibody analysis. The tumor cells, which do not grow spontaneously in vitro, were found to proliferate in all but one case in response to partially purified B cell growth factor (BCGF) without anti-mu or Sac activation. Recombinant interleukin 2 however produced only a marginal response and could not support leukemic cell growth in vitro. BCGF, however, did stimulate in vitro cell growth and supported the establishment of continuous (greater than 60 d in vitro) in four of the seven HCL cases.

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Year:  1985        PMID： 2993470      PMCID： PMC2187808          DOI： 10.1084/jem.162.3.1093

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  15 in total

1.  Tartrate-resistant acid phosphatase isoenzyme in the reticulum cells of leukemic reticuloendotheliosis.

Authors:  L T Yam; C Y Li; K W Lam
Journal:  N Engl J Med       Date:  1971-02-18       Impact factor: 91.245

2.  The monoclonal antibodies alpha S-HCL 1 (alpha Leu-14) and alpha S-HCL 3 (alpha Leu-M5) allow the diagnosis of hairy cell leukemia.

Authors:  R Schwarting; H Stein; C Y Wang
Journal:  Blood       Date:  1985-04       Impact factor: 22.113

3.  Long-term growth of human B cells and their use in a microassay for B-cell growth factor.

Authors:  A L Maizel; J W Morgan; S R Mehta; N M Kouttab; J M Bator; C G Sahasrabuddhe
Journal:  Proc Natl Acad Sci U S A       Date:  1983-08       Impact factor: 11.205

4.  Proliferation of human B lymphocytes mediated by a soluble factor.

Authors:  A Maizel; S Mehta; N Kouttab; J Morgan; R Ford; C Sahasrabuddhe
Journal:  Fed Proc       Date:  1983-07

5.  Soluble factor activation of human B lymphocytes.

Authors:  R J Ford; S R Mehta; D Franzini; R Montagna; L B Lachman; A L Maizel
Journal:  Nature       Date:  1981-11-19       Impact factor: 49.962

6.  A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor.

Authors:  W J Leonard; J M Depper; T Uchiyama; K A Smith; T A Waldmann; W C Greene
Journal:  Nature       Date:  1982-11-18       Impact factor: 49.962

7.  Biochemical separation of a human B cell mitogenic factor.

Authors:  A Maizel; C Sahasrabuddhe; S Mehta; J Morgan; L Lachman; R Ford
Journal:  Proc Natl Acad Sci U S A       Date:  1982-10       Impact factor: 11.205

8.  Monoclonal antibodies with specificity for hairy cell leukemia cells.

Authors:  D N Posnett; N Chiorazzi; H G Kunkel
Journal:  J Clin Invest       Date:  1982-08       Impact factor: 14.808

9.  Biological activity of recombinant human interleukin-2 produced in Escherichia coli.

Authors:  S A Rosenberg; E A Grimm; M McGrogan; M Doyle; E Kawasaki; K Koths; D F Mark
Journal:  Science       Date:  1984-03-30       Impact factor: 47.728

10.  Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia.

Authors:  S J Korsmeyer; W C Greene; J Cossman; S M Hsu; J P Jensen; L M Neckers; S L Marshall; A Bakhshi; J M Depper; W J Leonard; E S Jaffe; T A Waldmann
Journal:  Proc Natl Acad Sci U S A       Date:  1983-07       Impact factor: 11.205
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  7 in total

1.  Response of neoplasms of B cell lineage to the proliferative effects of B cell growth factor and the phorbol ester TPA.

Authors:  M C Kinney; R D Collins; J Whitlock; J B Cousar; L B Vogler
Journal:  Am J Pathol       Date:  1989-04       Impact factor: 4.307

2.  Modulation of the response to B-cell growth factor (BCGF) of hairy cells from a patient under IFN-alpha therapy.

Authors:  E Génot; C Mathiot; J P Kolb
Journal:  Blut       Date:  1987-07

3.  Establishment of Tac-negative, interleukin-2-dependent cytotoxic cell lines from large granular lymphocytes (LGL) of patients with expanded LGL populations.

Authors:  V Pistoia; A J Carroll; E F Prasthofer; A B Tilden; K S Zuckerman; M Ferrarini; C E Grossi
Journal:  J Clin Immunol       Date:  1986-11       Impact factor: 8.317

4.  Negative modulation of Epstein-Barr virus episomes by a human B-cell growth factor.

Authors:  J Morgan; A Roome; A Maizel; S Sharma
Journal:  J Virol       Date:  1989-07       Impact factor: 5.103

5.  Diagnostic and prognostic value of immunohistological bone marrow examination: results in 212 patients with lymphoproliferative disorders.

Authors:  J Thaler; H Denz; C Gattringer; H Glassl; M Lechleitner; O Dietze; H Huber
Journal:  Blut       Date:  1987-04

6.  Interleukin-6 functions as an intracellular growth factor in hairy cell leukemia in vitro.

Authors:  B Barut; D Chauhan; H Uchiyama; K C Anderson
Journal:  J Clin Invest       Date:  1993-11       Impact factor: 14.808

7.  Effects of interferon alpha on autocrine growth factor loops in B lymphoproliferative disorders.

Authors:  H E Heslop; A C Bianchi; F T Cordingley; M Turner; W Chandima; C P De Mel; A V Hoffbrand; M K Brenner
Journal:  J Exp Med       Date:  1990-12-01       Impact factor: 14.307
  7 in total

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