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Literature DB >> 2993242

Regulation of CDP-diacylglycerol synthase activity in Saccharomyces cerevisiae.

Abstract

The addition of ethanolamine or choline to inositol-containing growth medium resulted in a reduction of CTP:phosphatidate cytidylyltransferase (CDP-diacylglycerol synthase; EC 2.7.7.41) activity in Saccharomyces cerevisiae. The reduction of activity did not occur in the absence of inositol. CDP-diacylglycerol synthase activity was not regulated in a S. cerevisiae mutant strain (opi1; an inositol biosynthesis regulatory mutant) by the addition of phospholipid precursors to the growth medium.

Entities: Chemical Gene Species

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Year: 1985 PMID： 2993242 PMCID： PMC219270 DOI： 10.1128/jb.163.3.1265-1266.1985

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

15 in total

1. The function of cytidine coenzymes in the biosynthesis of phospholipides.

Authors: E P KENNEDY; S B WEISS
Journal: J Biol Chem Date: 1956-09 Impact factor: 5.157

2. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

Authors: M M Bradford
Journal: Anal Biochem Date: 1976-05-07 Impact factor: 3.365

3. Differential regulation of the N-methyl transferases responsible for phosphatidylcholine synthesis in Saccharomyces cerevisiae.

Authors: C J Waechter; R L Lester
Journal: Arch Biochem Biophys Date: 1973-09 Impact factor: 4.013

4. In vitro studies of phospholipid biosynthesis in Saccharomyces cerevisiae.

Authors: M R Steiner; R L Lester
Journal: Biochim Biophys Acta Date: 1972-02-21

5. CDP-diacylglycerol synthase activity in Clostridium perfringens.

Authors: G M Carman; R L Zaniewski; J J Cousminer
Journal: Appl Environ Microbiol Date: 1982-01 Impact factor: 4.792

6. Regulatory mutations of inositol biosynthesis in yeast: isolation of inositol-excreting mutants.

Authors: M L Greenberg; B Reiner; S A Henry
Journal: Genetics Date: 1982-01 Impact factor: 4.562

7. Utilization of endogenous diacylglycerol for the synthesis of triacylglycerol, phosphatidylcholine and phosphatidylethanolamine by lipid particles from baker's yeast (Saccharomyces cerevisiae).

Authors: K Christiansen
Journal: Biochim Biophys Acta Date: 1979-09-28

8. Properties of particulate and solubilized phosphatidylserine synthase activity from Saccharomyces cerevisiae. Inhibitory effect of choline in the growth medium.

Authors: M A Carson; K D Atkinson; C J Waechter
Journal: J Biol Chem Date: 1982-07-25 Impact factor: 5.157

9. Changes in phospholipids of Saccharomyces cerevisiae associated with inositol-less death.

Authors: G W Becker; R L Lester
Journal: J Biol Chem Date: 1977-12-10 Impact factor: 5.157

10. Coordinate regulation of phospholipid biosynthesis in Saccharomyces cerevisiae: pleiotropically constitutive opi1 mutant.

Authors: L S Klig; M J Homann; G M Carman; S A Henry
Journal: J Bacteriol Date: 1985-06 Impact factor: 3.490

24 in total

Regulation of CDP-diacylglycerol synthase activity in Saccharomyces cerevisiae.

1. The function of cytidine coenzymes in the biosynthesis of phospholipides.

2. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

3. Differential regulation of the N-methyl transferases responsible for phosphatidylcholine synthesis in Saccharomyces cerevisiae.

4. In vitro studies of phospholipid biosynthesis in Saccharomyces cerevisiae.

5. CDP-diacylglycerol synthase activity in Clostridium perfringens.

6. Regulatory mutations of inositol biosynthesis in yeast: isolation of inositol-excreting mutants.

7. Utilization of endogenous diacylglycerol for the synthesis of triacylglycerol, phosphatidylcholine and phosphatidylethanolamine by lipid particles from baker's yeast (Saccharomyces cerevisiae).

8. Properties of particulate and solubilized phosphatidylserine synthase activity from Saccharomyces cerevisiae. Inhibitory effect of choline in the growth medium.

9. Changes in phospholipids of Saccharomyces cerevisiae associated with inositol-less death.

10. Coordinate regulation of phospholipid biosynthesis in Saccharomyces cerevisiae: pleiotropically constitutive opi1 mutant.

Review 1. Regulation of phospholipid synthesis in the yeast Saccharomyces cerevisiae.

2. Analysis of sequences in the INO1 promoter that are involved in its regulation by phospholipid precursors.

3. Coordinate regulation of phosphatidylserine decarboxylase in Saccharomyces cerevisiae.

Review 4. Genetic regulation of phospholipid biosynthesis in Saccharomyces cerevisiae.

5. Regulation of phosphatidate phosphatase activity by inositol in Saccharomyces cerevisiae.

6. Regulation of phosphatidylinositol kinase activity in Saccharomyces cerevisiae.

7. Effect of growth phase on phospholipid biosynthesis in Saccharomyces cerevisiae.

Review 8. The response to inositol: regulation of glycerolipid metabolism and stress response signaling in yeast.

9. Regulation of yeast phospholipid biosynthetic genes in phosphatidylserine decarboxylase mutants.

Review 10. Regulation of phospholipid synthesis in yeast.