Literature DB >> 29931555

Uric acid and progression of chronic kidney disease.

Donald J Weaver1.   

Abstract

The association between serum uric acid levels and human disease has garnered intense interest over the last decade including chronic kidney disease. Animal studies have provided evidence for a potential mechanistic role of uric acid in promoting progression of chronic kidney disease. Epidemiologic studies have also suggested an association between elevated serum uric acid levels and worsening renal function in the general population as well as in patients with chronic kidney disease. However, there is currently insufficient evidence to recommend the use of uric acid-lowering therapy to delay progression of chronic kidney disease in this patient population. Adequately powered, randomized, placebo-controlled trials are required to more precisely evaluate the risk and benefits of uric acid-lowering therapy in pediatric patients.

Entities:  

Keywords:  Allopurinol; Chronic kidney disease; Hypertension; Uric acid; Xanthine oxidoreductase

Mesh：

Substances：

Year:  2018        PMID： 29931555     DOI： 10.1007/s00467-018-3979-2

Source DB:  PubMed          Journal:  Pediatr Nephrol        ISSN： 0931-041X            Impact factor:   3.714


  61 in total

1.  Association of hyperuricemia with renal outcomes, cardiovascular disease, and mortality.

Authors:  Wan-Chun Liu; Chi-Chih Hung; Szu-Chia Chen; Shih-Meng Yeh; Ming-Yen Lin; Yi-Wen Chiu; Mei-Chuan Kuo; Jer-Ming Chang; Shang-Jyh Hwang; Hung-Chun Chen
Journal:  Clin J Am Soc Nephrol       Date:  2012-02-02       Impact factor: 8.237

2.  Use of allopurinol in slowing the progression of renal disease through its ability to lower serum uric acid level.

Authors:  Yui-Pong Siu; Kay-Tai Leung; Matthew Ka-Hang Tong; Tze-Hoi Kwan
Journal:  Am J Kidney Dis       Date:  2006-01       Impact factor: 8.860

3.  Uric acid levels, kidney function, and cardiovascular mortality in US adults: National Health and Nutrition Examination Survey (NHANES) 1988-1994 and 1999-2002.

Authors:  Michelle C Odden; Abdul-Razak Amadu; Ellen Smit; Lowell Lo; Carmen A Peralta
Journal:  Am J Kidney Dis       Date:  2014-06-04       Impact factor: 8.860

4.  Uric acid inhibits renal proximal tubule cell proliferation via at least two signaling pathways involving PKC, MAPK, cPLA2, and NF-kappaB.

Authors:  Ho Jae Han; Min Jin Lim; Yun Jung Lee; Jang Hern Lee; Il Suk Yang; Mary Taub
Journal:  Am J Physiol Renal Physiol       Date:  2006-09-19

5.  Effect of allopurinol in decreasing proteinuria in type 2 diabetic patients.

Authors:  Ali Momeni; Shahrzad Shahidi; Shiva Seirafian; Shahram Taheri; Soleiman Kheiri
Journal:  Iran J Kidney Dis       Date:  2010-04       Impact factor: 0.892

Review 6.  Hyperuricemia, Hypertension, and Chronic Kidney Disease: an Emerging Association.

Authors:  Samir G Mallat; Sahar Al Kattar; Bassem Y Tanios; Abdo Jurjus
Journal:  Curr Hypertens Rep       Date:  2016-10       Impact factor: 5.369

7.  Uric acid-induced phenotypic transition of renal tubular cells as a novel mechanism of chronic kidney disease.

Authors:  Eun-Sun Ryu; Mi Jin Kim; Hyun-Soo Shin; Yang-Hee Jang; Hack Sun Choi; Inho Jo; Richard J Johnson; Duk-Hee Kang
Journal:  Am J Physiol Renal Physiol       Date:  2013-01-02

8.  Elevated uric acid increases the risk for kidney disease.

Authors:  Rudolf P Obermayr; Christian Temml; Georg Gutjahr; Maarten Knechtelsdorfer; Rainer Oberbauer; Renate Klauser-Braun
Journal:  J Am Soc Nephrol       Date:  2008-09-17       Impact factor: 10.121

9.  Uric acid stimulates vascular smooth muscle cell proliferation and oxidative stress via the vascular renin-angiotensin system.

Authors:  Dalila B Corry; Pirooz Eslami; Kei Yamamoto; Michael D Nyby; Hirofumi Makino; Michael L Tuck
Journal:  J Hypertens       Date:  2008-02       Impact factor: 4.844

10.  Serum Uric Acid and Risk of CKD in Type 2 Diabetes.

Authors:  Salvatore De Cosmo; Francesca Viazzi; Antonio Pacilli; Carlo Giorda; Antonio Ceriello; Sandro Gentile; Giuseppina Russo; Maria C Rossi; Antonio Nicolucci; Pietro Guida; Daniel Feig; Richard J Johnson; Roberto Pontremoli
Journal:  Clin J Am Soc Nephrol       Date:  2015-09-04       Impact factor: 8.237
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  5 in total

1.  Hyperuricemia: an unrecognized risk factor for kidney-related sequelae in children with hemolytic uremic syndrome.

Authors:  Alejandro Balestracci; Luciana Meni Battaglia; Ismael Toledo; Laura Beaudoin; Sandra Mariel Martin; Nicolás Ariel Grisolía; Ronald J Hogg
Journal:  Pediatr Nephrol       Date:  2022-10-13       Impact factor: 3.651

2.  Hyperuricemia and hypertriglyceridemia indicate tubular atrophy/interstitial fibrosis in patients with IgA nephropathy and membranous nephropathy.

Authors:  Bingman Liu; Liangyu Zhao; Qingqing Yang; Dongqing Zha; Xiaoyun Si
Journal:  Int Urol Nephrol       Date:  2021-04-24       Impact factor: 2.370

Review 3.  An evaluation of the roles of hematuria and uric acid in defining the prognosis of patients with IgA nephropathy.

Authors:  Ron Hogg
Journal:  Pediatr Nephrol       Date:  2021-05-13       Impact factor: 3.714

4.  The Effects of Febuxostat on Urine NGAL and Urine KIM-1 in Patients with Hyperuricemia.

Authors:  Yushang Tang; Tongqiang Liu; Qiuping Cai; Minwen Zhao
Journal:  J Healthc Eng       Date:  2022-04-04       Impact factor: 2.682

5.  Effect Modification of Hyperuricemia, Cardiovascular Risk, and Age on Chronic Kidney Disease in China: A Cross-Sectional Study Based on the China Health and Nutrition Survey Cohort.

Authors:  Yang Li; Bowen Zhu; Yeqing Xie; Shi Jin; Weiran Zhou; Yi Fang; Xiaoqiang Ding
Journal:  Front Cardiovasc Med       Date:  2022-03-07
  5 in total

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