Literature DB >> 29928099

Nilotinib induced avascular necrosis of femoral head in an adult chronic myeloid leukemia patient.

Shinto Francis Thekkudan1, Soniya Nityanand1.   

Abstract

We report a rare case of avascular necrosis of femoral head (AVNFH) in an adult chronic myeloid leukemia - chronic phase (CML-CP) patient during due course of therapy with second line Tyrosine Kinase Inhibitor (TKI), Nilotinib. A high index of clinical suspicion should be kept in any symptomatic CML patient on TKI's.

Entities:  

Keywords:  ANA, Anti nuclear antibody; AP, Accelerated phase; AVNFH, Avascular necrosis of femoral head; Avascular necrosis of femoral head; CCR, Complete cytological response; CHR, Complete hematological response; CML, Chronic myeloid leukemia; CP, Chronic phase; Chronic myeloid leukemia; IS, International scale; MMR, Major Molecular response; Nilotinib; TKI, Tyrosine kinase inhibitor; Tyrosine kinase inhibitor; qPCR, Quantitative polymerase chain reaction

Year:  2017        PMID： 29928099      PMCID： PMC6008635          DOI： 10.1016/j.jcot.2017.11.015

Source DB:  PubMed          Journal:  J Clin Orthop Trauma        ISSN： 0976-5662


  9 in total

1.  Imatinib-induced avascular necrosis of femur in childhood chronic myeloid leukemia.

Authors:  Vijayamurugan Nataraj; Devasenathepathy Kandasamy; Sameer Bakhshi
Journal:  Pediatr Hematol Oncol       Date:  2014-01-02       Impact factor: 1.969

2.  Avascular necrosis of femoral head as the initial manifestation of CML.

Authors:  Suresh Kumar; Deepak Bansal; Mahesh Prakash; Prashant Sharma
Journal:  Pediatr Hematol Oncol       Date:  2013-10-02       Impact factor: 1.969

3.  Is avascular necrosis of the femoral head the result of inhibition of angiogenesis?

Authors:  D W Smith
Journal:  Med Hypotheses       Date:  1997-12       Impact factor: 1.538

4.  Avascular necrosis of the femoral head in chronic myeloid leukemia patients treated with interferon-alpha: a synergistic correlation?

Authors:  P Kozuch; M Talpaz; S Faderl; S O'Brien; E J Freireich; H Kantarjian
Journal:  Cancer       Date:  2000-10-01       Impact factor: 6.860

5.  Avascular necrosis of the femoral head as a complication of chronic myelogenous leukaemia.

Authors:  J Leone; J P Vilque; B Pignon; C Marcus; J L Pennaforte; J P Eschard; J C Etienne
Journal:  Skeletal Radiol       Date:  1996-10       Impact factor: 2.199

6.  Chronic myeloid leukemia presenting with avascular necrosis of femur head.

Authors:  D Gupta; M Gaiha; N Siddaraju; M K Daga; S Anuradha
Journal:  J Assoc Physicians India       Date:  2003-02

7.  Avascular bone necrosis in an untreated case of chronic myelogenous leukemia.

Authors:  Z Salimi; W Vas; M Sundaram
Journal:  Skeletal Radiol       Date:  1988       Impact factor: 2.199

8.  Chronic myeloid leukaemia presenting as femoral head necrosis.

Authors:  J Gibson; D E Joshua; D Collis; H Kronenberg
Journal:  Scand J Haematol       Date:  1984-04

9.  Dasatinib Induced Avascular Necrosis of Femoral Head in Adult Patient with Chronic Myeloid Leukemia.

Authors:  Mohamed A Yassin; Abbas H Moustafa; Abdulqadir J Nashwan; Ashraf T Soliman; Hatim El Derhoubi; Shehab F Mohamed; Deena S Mudawi; Sarah ELkourashy; Deena-Raiza Asaari; Hope-Love G Gutierrez; Radwa M Hussein; Mohamed Al Musharraf; Samah Kohla; Ahmed Elsayed; Nader Al-Dewik
Journal:  Clin Med Insights Blood Disord       Date:  2015-07-23
  9 in total
  2 in total

1.  Avascular necrosis in patients with chronic myeloid leukemia: A systematic review.

Authors:  Mohamed Yassin; Abdulrahman F Al-Mashdali; Husam N Al-Dubai
Journal:  Acta Biomed       Date:  2022-03-14

Review 2.  Osteonecrosis of the Femoral Head in Patients with Hypercoagulability-From Pathophysiology to Therapeutic Implications.

Authors:  Elena Rezus; Bogdan Ionel Tamba; Minerva Codruta Badescu; Diana Popescu; Ioana Bratoiu; Ciprian Rezus
Journal:  Int J Mol Sci       Date:  2021-06-24       Impact factor: 5.923
  2 in total

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