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Literature DB >> 29927612

Reactive Oxygen Species-Triggered Tunable Hydrogen Sulfide Release.

Preeti Chauhan¹, Swetha Jos¹, Harinath Chakrapani¹.

Abstract

A series of carbamothioates with tunable release of H2S after activation by reactive oxygen species are reported. The half-lives of H2S release could be tuned from 24 to 203 min by varying the basicity of the amine.

Entities: Chemical

Year: 2018 PMID： 29927612 DOI： 10.1021/acs.orglett.8b01356

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

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Cited

13 in total

1. Alleviating Cellular Oxidative Stress through Treatment with Superoxide-Triggered Persulfide Prodrugs.

Authors: Yin Wang; Kearsley M Dillon; Zhao Li; Ethan W Winckler; John B Matson
Journal: Angew Chem Int Ed Engl Date: 2020-07-23 Impact factor: 15.336

2. H₂S donors with optical responses.

Authors: Michael D Pluth; Yu Zhao; Matthew M Cerda
Journal: Methods Enzymol Date: 2020-06-15 Impact factor: 1.600

3. Development of Acid-Mediated H₂S/COS Donors That Respond to a Specific pH Window.

Authors: Annie K Gilbert; Yu Zhao; Claire E Otteson; Michael D Pluth
Journal: J Org Chem Date: 2019-09-18 Impact factor: 4.354

Review 4. Activatable Small-Molecule Hydrogen Sulfide Donors.

Authors: Carolyn M Levinn; Matthew M Cerda; Michael D Pluth
Journal: Antioxid Redox Signal Date: 2019-10-29 Impact factor: 8.401

Review 5. Prodrug strategies for targeted therapy triggered by reactive oxygen species.

Authors: Jorge Peiró Cadahía; Viola Previtali; Nikolaj S Troelsen; Mads H Clausen
Journal: Medchemcomm Date: 2019-05-08 Impact factor: 3.597

6. Cyclic Sulfenyl Thiocarbamates Release Carbonyl Sulfide and Hydrogen Sulfide Independently in Thiol-Promoted Pathways.

Authors: Yu Zhao; Andrea K Steiger; Michael D Pluth
Journal: J Am Chem Soc Date: 2019-08-14 Impact factor: 15.419

Reactive Oxygen Species-Triggered Tunable Hydrogen Sulfide Release.

1. Alleviating Cellular Oxidative Stress through Treatment with Superoxide-Triggered Persulfide Prodrugs.

2. H₂S donors with optical responses.

3. Development of Acid-Mediated H₂S/COS Donors That Respond to a Specific pH Window.

Review 4. Activatable Small-Molecule Hydrogen Sulfide Donors.

Review 5. Prodrug strategies for targeted therapy triggered by reactive oxygen species.

6. Cyclic Sulfenyl Thiocarbamates Release Carbonyl Sulfide and Hydrogen Sulfide Independently in Thiol-Promoted Pathways.

7. Use of Dithiasuccinoyl-Caged Amines Enables COS/H₂ S Release Lacking Electrophilic Byproducts.

8. Colorimetric Carbonyl Sulfide (COS)/Hydrogen Sulfide (H₂ S) Donation from γ-Ketothiocarbamate Donor Motifs.

9. N-Methylation of Self-Immolative Thiocarbamates Provides Insights into the Mechanism of Carbonyl Sulfide Release.

Review 10. Moving Past Quinone-Methides: Recent Advances Toward Minimizing Electrophilic Byproducts from COS/H₂S Donors.

Review 4. Activatable Small-Molecule Hydrogen Sulfide Donors.

Review 5. Prodrug strategies for targeted therapy triggered by reactive oxygen species.

Review 10. Moving Past Quinone-Methides: Recent Advances Toward Minimizing Electrophilic Byproducts from COS/H2S Donors.

Review 10. Moving Past Quinone-Methides: Recent Advances Toward Minimizing Electrophilic Byproducts from COS/H₂S Donors.