Literature DB >> 29927098

Development of a Three-Dimensional Bioengineering Technology to Generate Lung Tissue for Personalized Disease Modeling.

Dan C Wilkinson1, Michael Mellody2, Luisa K Meneses3, Ashley C Hope3, Bruce Dunn1, Brigitte N Gomperts3,4,5,6.   

Abstract

This unit describes a protocol for generation of lung organoids. A lung organoid is a 3D cell/hydrogel composite that resembles the morphology and cellular composition of the human distal lung. These tissue-engineered constructs provide an in vitro model of human lung and are best suited for disease modeling applications. The organoid generation methodology is flexible, allowing for easy scalability in the number of organoids produced and in the ability to accommodate a wide range of cell types.
© 2018 by John Wiley & Sons, Inc. © 2018 John Wiley & Sons, Inc.

Entities:  

Keywords:  3-D cell culture; distal airway; lung disease modeling; pluripotent stem cells; tissue engineering

Mesh：

Substances：

Year:  2018        PMID： 29927098      PMCID： PMC6105393          DOI： 10.1002/cpsc.56

Source DB:  PubMed          Journal:  Curr Protoc Stem Cell Biol        ISSN： 1938-8969


  7 in total

Review 1.  Human stem cells and drug screening: opportunities and challenges.

Authors:  Allison D Ebert; Clive N Svendsen
Journal:  Nat Rev Drug Discov       Date:  2010-03-26       Impact factor: 84.694

Review 2.  Gene expression perturbation in vitro--a growing case for three-dimensional (3D) culture systems.

Authors:  Anna Birgersdotter; Rickard Sandberg; Ingemar Ernberg
Journal:  Semin Cancer Biol       Date:  2005-10       Impact factor: 15.707

Review 3.  Three-dimensional cell culture matrices: state of the art.

Authors:  Jungwoo Lee; Meghan J Cuddihy; Nicholas A Kotov
Journal:  Tissue Eng Part B Rev       Date:  2008-03       Impact factor: 6.389

Review 4.  The burden of idiopathic pulmonary fibrosis: an unmet public health need.

Authors:  Augustine S Lee; Isabella Mira-Avendano; Jay H Ryu; Craig E Daniels
Journal:  Respir Med       Date:  2014-04-13       Impact factor: 3.415

5.  Mussel-inspired surface chemistry for multifunctional coatings.

Authors:  Haeshin Lee; Shara M Dellatore; William M Miller; Phillip B Messersmith
Journal:  Science       Date:  2007-10-19       Impact factor: 47.728

6.  Engineering de novo assembly of fetal pulmonary organoids.

Authors:  Mark J Mondrinos; Peter L Jones; Christine M Finck; Peter I Lelkes
Journal:  Tissue Eng Part A       Date:  2014-06-25       Impact factor: 3.845

7.  Fibroblasts derived from human pluripotent stem cells activate angiogenic responses in vitro and in vivo.

Authors:  Yulia Shamis; Eduardo A Silva; Kyle J Hewitt; Yevgeny Brudno; Shulamit Levenberg; David J Mooney; Jonathan A Garlick
Journal:  PLoS One       Date:  2013-12-30       Impact factor: 3.240
  7 in total
  5 in total

1.  The Optimization of a Novel Hydrogel-Egg White-Alginate for 2.5D Tissue Engineering of Salivary Spheroid-Like Structure.

Authors:  Yuli Zhang; Hieu M Pham; Jose G Munguia-Lopez; Joseph M Kinsella; Simon D Tran
Journal:  Molecules       Date:  2020-12-06       Impact factor: 4.411

2.  Development of a Decellularized Porcine Esophageal Matrix for Potential Applications in Cancer Modeling.

Authors:  Hersh Chaitin; Michael L Lu; Michael B Wallace; Yunqing Kang
Journal:  Cells       Date:  2021-04-29       Impact factor: 6.600

Review 3.  Application of iPSC to Modelling of Respiratory Diseases.

Authors:  Ben A Calvert; Amy L Ryan Firth
Journal:  Adv Exp Med Biol       Date:  2020       Impact factor: 2.622

Review 4.  Towards organoid culture without Matrigel.

Authors:  Mark T Kozlowski; Christiana J Crook; Hsun Teresa Ku
Journal:  Commun Biol       Date:  2021-12-10

Review 5.  Regenerative Medicine in COVID-19 Treatment: Real Opportunities and Range of Promises.

Authors:  Arefeh Basiri; Zahra Pazhouhnia; Nima Beheshtizadeh; Mahdieh Hoseinpour; Amene Saghazadeh; Nima Rezaei
Journal:  Stem Cell Rev Rep       Date:  2021-02       Impact factor: 5.739
  5 in total

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