Literature DB >> 2992681

Hyperexcitability following moderate hypoxia in hippocampal tissue slices.

S J Schiff, G G Somjen.   

Abstract

The effects of moderate hypoxia on CA1 pyramidal cells were studied in submerged rat hippocampal tissue slices. Hyperexcitability developed during re-oxygenation following 30-45 min of hypoxia at 29 degrees C. During hypoxia a sustained increase in extracellular potassium was observed. The post-hypoxic hyperexcitability of CA1 neurons may be the result of their inability to fully recover intracellular potassium lost during oxygen deprivation.

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Year:  1985        PMID： 2992681     DOI： 10.1016/0006-8993(85)90071-x

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  14 in total

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2.  Mesencephalic stimulation elicits inhibition of phrenic nerve activity in cat.

Authors:  E A Gallman; W L Lawing; D E Millhorn
Journal:  J Physiol       Date:  1991-05       Impact factor: 5.182

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4.  Expression of Nampt in hippocampal and cortical excitatory neurons is critical for cognitive function.

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5.  Dorsolateral prefrontal cortex GABA deficit in older adults with sleep-disordered breathing.

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6.  Effects of antenatal magnesium sulfate treatment on cerebral blood flow velocities in preterm neonates.

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7.  Acidosis and blockade of orthodromic responses caused by anoxia in rat hippocampal slices at different temperatures.

Authors:  K Krnjević; W Walz
Journal:  J Physiol       Date:  1990-03       Impact factor: 5.182

8.  Decreased calcium-activated potassium channels by hypoxia causes abnormal firing in the spontaneous firing medial vestibular nuclei neurons.

Authors:  Hong Xie; Yu-qin Zhang; Xin-liang Pan; Shu-hui Wu; Xiang Chen; Jie Wang; Hua Liu; Xiao-zhong Qian; Zhi-guo Liu; Lie-Ju Liu
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-08-31       Impact factor: 2.503

9.  Two long-lasting central respiratory responses following acute hypoxia in glomectomized cats.

Authors:  E A Gallman; D E Millhorn
Journal:  J Physiol       Date:  1988-01       Impact factor: 5.182

10.  Oxygen and seizure dynamics: I. Experiments.

Authors:  Justin Ingram; Chunfeng Zhang; John R Cressman; Anupam Hazra; Yina Wei; Yong-Eun Koo; Jokūbas Žiburkus; Raoul Kopelman; Jian Xu; Steven J Schiff
Journal:  J Neurophysiol       Date:  2014-03-05       Impact factor: 2.714
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