| Literature DB >> 29926447 |
Andrea Idili1, Francesco Ricci2.
Abstract
Triplex DNA is becoming a very useful domain to design pH-triggered DNA nanoswitches and nanodevices. The high versatility and programmability of triplex DNA interactions allows the integration of pH-controllable modules into DNA-based reactions and self-assembly processes. Here, we describe the procedure to characterize DNA-based triplex nanoswitches and more in general pH-triggered structure-switching mechanisms. Procedures to characterize pH-triggered DNA nanodevices will be useful for many applications in the field of biosensing, drug delivery systems and smart nanomaterials.Keywords: DNA nanostructures; Nanoswitches; Triple helix; pH switching
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Year: 2018 PMID: 29926447 DOI: 10.1007/978-1-4939-8582-1_6
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745