Literature DB >> 2992564

Effects of nicardipine on aldosterone release and pressor mechanisms.

H L Elliott, F Pasanisi, J L Reid.   

Abstract

This study evaluated the effects of nicardipine, following intravenous infusion and oral administration, on the pressor and aldosterone responses to infused angiotensin II. Six healthy, normotensive male subjects were studied. Following administration of nicardipine, no significant change in blood pressure was seen. Nicardipine attenuated the pressor response produced by intravenous administration of angiotensin. Nicardipine did not inhibit the aldosterone response to angiotensin.

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Year:  1985        PMID： 2992564      PMCID： PMC1400791          DOI： 10.1111/j.1365-2125.1985.tb05150.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  15 in total

1.  A sensitive radioenzymatic assay for norepinephrine in tissues and plasma.

Authors:  D P Henry; B J Starman; D G Johnson; R H Williams
Journal:  Life Sci       Date:  1975-02-01       Impact factor: 5.037

2.  STIMULUS-SECRETION COUPLING IN A NEUROSECRETORY ORGAN: THE ROLE OF CALCIUM IN THE RELEASE OF VASOPRESSIN FROM THE NEUROHYPOPHYSIS.

Authors:  W W DOUGLAS; A M POISNER
Journal:  J Physiol       Date:  1964-07       Impact factor: 5.182

3.  The mechanism of catecholamine release from the adrenal medulla and the role of calcium in stimulus-secretion coupling.

Authors:  W W Douglas; R P Rubin
Journal:  J Physiol       Date:  1963-07       Impact factor: 5.182

4.  On the role of calcium in adrenocorticotropin-induced changes in mitochondrial pregnenolone synthesis.

Authors:  R V Farese; W J Prudente
Journal:  Endocrinology       Date:  1978-10       Impact factor: 4.736

5.  Studies on cyclic nucleotides in the adrenal gland. VIII. Effects of angiotensin on adenosine 3',5'-monophosphate and steroidogenesis in the adrenal cortex.

Authors:  S Shima; Y Kawashima; M Hirai
Journal:  Endocrinology       Date:  1978-10       Impact factor: 4.736

6.  The relation of arterial pressure and plasma angiotensin II concentration. A change produced by prolonged infusion of angiotensin II in the conscious dog.

Authors:  B L Bean; J J Brown; J Casals-Stenzel; R Fraser; A F Lever; J A Millar; J J Morton; B Petch; A J Riegger; J I Robertson; M Tree
Journal:  Circ Res       Date:  1979-04       Impact factor: 17.367

7.  Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension.

Authors:  K Hiramatsu; F Yamagishi; T Kubota; T Yamada
Journal:  Am Heart J       Date:  1982-12       Impact factor: 4.749

8.  Dependence of aldosterone stimulation in adrenal glomerulosa cells on calcium uptake: effects of lanthanum nd verapamil.

Authors:  J L Fakunding; K J Catt
Journal:  Endocrinology       Date:  1980-11       Impact factor: 4.736

9.  Effect of nifedipine on blood pressure and adrenocortical responses to trophic stimuli in humans.

Authors:  J A Millar; A D Struthers; G H Beastall; J L Reid
Journal:  J Cardiovasc Pharmacol       Date:  1982       Impact factor: 3.105

10.  Reduced pressor effect of angiotensin II and of noradrenaline in normal man following the oral administration of the calcium-antagonist nifedipine.

Authors:  H Vierhapper; W Waldhäusl
Journal:  Eur J Clin Invest       Date:  1982-06       Impact factor: 4.686
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  2 in total

Review 1.  Molecular and clinical investigations in patients with low-renin hypertension.

Authors:  Isla S Mackenzie; Morris J Brown
Journal:  Clin Exp Nephrol       Date:  2008-08-15       Impact factor: 2.801

Review 2.  Nicardipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in the treatment of angina pectoris, hypertension and related cardiovascular disorders.

Authors:  E M Sorkin; S P Clissold
Journal:  Drugs       Date:  1987-04       Impact factor: 9.546
  2 in total

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