Literature DB >> 29925558

Case of severe acute lupus myocarditis and multiple-organ failure.

Aaron M Hawkins1,2, Lalith S B Jesuthasan3, Deepak L Vardesh1,2.   

Abstract

We report a case of severe lupus myocarditis with rapid, acute deterioration to cardiogenic shock and multiorgan failure, highlighting the importance of early identification and treatment of acute presentations in patients with systemic lupus erythematosus. A 31-year-old woman with previously diagnosed subacute cutaneous lupus erythematosus initially presented with abdominal pain and frank per-rectal bleeding. She deteriorated rapidly with type 1 respiratory failure and acute kidney injury requiring dialysis secondary to acute cardiac failure with a prolonged intensive care unit admission, over a month. A significantly elevated troponin, global hypokinesia on echocardiogram and normal coronary artery angiogram and cardiac MRI lead to the diagnosis of acute lupus myocarditis as the cause for the cardiogenic shock. She was treated with high-dose corticosteroids and eventually made a full recovery, with cardiac function returning to normal. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  acute renal failure; cardiovascular medicine; rheumatology

Mesh:

Year:  2018        PMID: 29925558      PMCID: PMC6011492          DOI: 10.1136/bcr-2018-225085

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  15 in total

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Journal:  J Clin Gastroenterol       Date:  2011 May-Jun       Impact factor: 3.062

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Journal:  Arthritis Rheum       Date:  2012-08

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Authors:  Diane L Kamen; Charlie Strange
Journal:  Clin Chest Med       Date:  2010-09       Impact factor: 2.878

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Journal:  Postgrad Med J       Date:  2004-06       Impact factor: 2.401

Review 7.  Arrhythmias and conduction defects in rheumatological diseases--a comprehensive review.

Authors:  Alon Eisen; Yoav Arnson; Zamir Dovrish; Ruthy Hadary; Howard Amital
Journal:  Semin Arthritis Rheum       Date:  2008-06-30       Impact factor: 5.532

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Authors:  K Sandrasegaran; C W Clarke; V Nagendran
Journal:  Postgrad Med J       Date:  1992-06       Impact factor: 2.401

9.  Morbidity and mortality in systemic lupus erythematosus during a 10-year period: a comparison of early and late manifestations in a cohort of 1,000 patients.

Authors:  Ricard Cervera; Munther A Khamashta; Josep Font; Gian Domenico Sebastiani; Antonio Gil; Paz Lavilla; Juan Carlos Mejía; A Olcay Aydintug; Hanna Chwalinska-Sadowska; Enrique de Ramón; Antonio Fernández-Nebro; Mauro Galeazzi; Merete Valen; Alessandro Mathieu; Frédéric Houssiau; Natividad Caro; Paula Alba; Manuel Ramos-Casals; Miguel Ingelmo; Graham R V Hughes
Journal:  Medicine (Baltimore)       Date:  2003-09       Impact factor: 1.889

10.  Pharmacodynamic monitoring of (immuno)proteasome inhibition during bortezomib treatment of a critically ill patient with lupus nephritis and myocarditis.

Authors:  Karina A de Groot; Michel Tsang A Sjoe; Denise Niewerth; Jacqueline Cloos; Jonathan L Blank; Hans W M Niessen; Sonja Zweegman; Alexandre E Voskuyl; Gerrit Jansen; Joost W van der Heijden
Journal:  Lupus Sci Med       Date:  2015-12-18
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  1 in total

1.  Cardiac Complications Attributed to Hydroxychloroquine: A Systematic Review of the Literature Pre-COVID-19.

Authors:  Georgi Fram; Dee D Wang; Kelly Malette; Pedro Villablanca; Guson Kang; Kent So; Mir B Basir; Arfaat Khan; John E McKinnon; Marcus Zervos; William W O'Neill
Journal:  Curr Cardiol Rev       Date:  2021
  1 in total

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