F Essiben1, P Foumane1,2, E T Mboudou1,2, J S Dohbit1,2, V Mve Koh3, P Ndom1. 1. Département de Gynécologie-Obstétrique, Faculté de Médecine et des Sciences Biomédicales, Université de Yaoundé 1, Cameroun. 2. Service de Gynécologie-Obstétrique, Hôpital Gynéco-Obstétrique et Pédiatrique de Yaoundé, Cameroun. 3. Faculté de Médecine et des Sciences Pharmaceutiques, Université de Douala, Cameroun.
Abstract
AIM: The objective was to describe the clinical and therapeutic aspects of breast cancer at the Yaounde Gynaeco-Obstetric and Pediatric Hospital, which is a referral centre for gynecological malignancies. METHODS: It was a retrospective descriptive study over a period of four years, from June 1st 2003 to May 31st 2007. RESULTS: Sixty five patients were identified during the study period. The mean age and parity were respectively 42.9 ±13.6 years and 3.9 ± 2.1. The mean age of onset of the first menses was 14.0 ± 1.5 years. Most patients were under 50 (72.3%) and had given birth at least once (89.2%). Non menopausal period (75.4%) and breastfeeding (76.9%) were frequently found. The patients consulted 9.2 ± 3.4 months after the onset of symptoms, with 78.5% of cases arriving at a local advanced clinical stage. Ductal carcinoma accounted for 75.4% of histological types, SBR grades 1 and 2 being the most frequent (89.2%). Chemotherapy (69.2% of the cases) and surgery (67.7% of the cases) often radical (three out of four) were the main treatment modalities used. CONCLUSION: In Yaounde, breast cancer is often a ductal carcinoma of high histological grade, attacking the quarantine non menopausal woman, who gave birth and breastfed at least once, diagnosed with a local clinical advanced disease. Chemotherapy and surgery are the main therapeutic options implemented. Le comitée de rédaction se réserve le droit de revoyer aux auteurs avant toute soumission à l'avis des lecteurs les manuscrits qui ne seraient pas conformes à ces modalités de présentation. En outre il leur conseille de sonserver un examplaire du manuscrit, des figures et des tableaux.
AIM: The objective was to describe the clinical and therapeutic aspects of breast cancer at the Yaounde Gynaeco-Obstetric and Pediatric Hospital, which is a referral centre for gynecological malignancies. METHODS: It was a retrospective descriptive study over a period of four years, from June 1st 2003 to May 31st 2007. RESULTS: Sixty five patients were identified during the study period. The mean age and parity were respectively 42.9 ±13.6 years and 3.9 ± 2.1. The mean age of onset of the first menses was 14.0 ± 1.5 years. Most patients were under 50 (72.3%) and had given birth at least once (89.2%). Non menopausal period (75.4%) and breastfeeding (76.9%) were frequently found. The patients consulted 9.2 ± 3.4 months after the onset of symptoms, with 78.5% of cases arriving at a local advanced clinical stage. Ductal carcinoma accounted for 75.4% of histological types, SBR grades 1 and 2 being the most frequent (89.2%). Chemotherapy (69.2% of the cases) and surgery (67.7% of the cases) often radical (three out of four) were the main treatment modalities used. CONCLUSION: In Yaounde, breast cancer is often a ductal carcinoma of high histological grade, attacking the quarantine non menopausal woman, who gave birth and breastfed at least once, diagnosed with a local clinical advanced disease. Chemotherapy and surgery are the main therapeutic options implemented. Le comitée de rédaction se réserve le droit de revoyer aux auteurs avant toute soumission à l'avis des lecteurs les manuscrits qui ne seraient pas conformes à ces modalités de présentation. En outre il leur conseille de sonserver un examplaire du manuscrit, des figures et des tableaux.
Entities:
Keywords:
Breast cancer; Cameroon; Cameroun; Cancer du sein; Diagnosis; Diagnostic; Traitement; Treatment