Literature DB >> 29924973

Immune Checkpoint Blockade across the Cancer Care Continuum.

Beth A Helmink1, Pierre-Olivier Gaudreau2, Jennifer A Wargo3.   

Abstract

Four studies recently reported in the New England Journal of Medicine highlight advances in treatment with immune checkpoint blockade across the cancer care continuum. These findings demonstrate efficacy of these agents in the treatment of early and late-stage disease, as monotherapy or in combination, and in addition to-or in place of-standard front-line therapy.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID: 29924973     DOI: 10.1016/j.immuni.2018.06.003

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  7 in total

1.  Tumor-infiltrating mesenchymal stem cells: Drivers of the immunosuppressive tumor microenvironment in prostate cancer?

Authors:  Timothy E Krueger; Daniel L J Thorek; Alan K Meeker; John T Isaacs; W Nathaniel Brennen
Journal:  Prostate       Date:  2018-11-28       Impact factor: 4.104

2.  Targeting IL-21 to tumor-reactive T cells enhances memory T cell responses and anti-PD-1 antibody therapy.

Authors:  Ying Li; Yanni Cong; Mingming Jia; Qianqian He; Haiqing Zhong; Yun Zhao; Hang Li; Meining Yan; Jia You; Jia Liu; Lieping Chen; Haiying Hang; Shengdian Wang
Journal:  Nat Commun       Date:  2021-02-11       Impact factor: 14.919

Review 3.  Microbiome Crosstalk in Immunotherapy and Antiangiogenesis Therapy.

Authors:  Xueting Wan; Mengyao Song; Aiyun Wang; Yang Zhao; Zhonghong Wei; Yin Lu
Journal:  Front Immunol       Date:  2021-10-21       Impact factor: 8.786

Review 4.  Understanding genomics and the immune environment of penile cancer to improve therapy.

Authors:  Ahmet Murat Aydin; Jad Chahoud; Jacob J Adashek; Mounsif Azizi; Anthony Magliocco; Jeffrey S Ross; Andrea Necchi; Philippe E Spiess
Journal:  Nat Rev Urol       Date:  2020-08-18       Impact factor: 14.432

Review 5.  Ang2 inhibitors and Tie2 activators: potential therapeutics in perioperative treatment of early stage cancer.

Authors:  Kabir A Khan; Florence Th Wu; William Cruz-Munoz; Robert S Kerbel
Journal:  EMBO Mol Med       Date:  2021-06-14       Impact factor: 12.137

Review 6.  Comparative Approach to the Temporo-Spatial Organization of the Tumor Microenvironment.

Authors:  Kendall L Langsten; Jong Hyuk Kim; Aaron L Sarver; Mark Dewhirst; Jaime F Modiano
Journal:  Front Oncol       Date:  2019-11-07       Impact factor: 6.244

Review 7.  NK Cell-Based Immune Checkpoint Inhibition.

Authors:  Muhammad Khan; Sumbal Arooj; Hua Wang
Journal:  Front Immunol       Date:  2020-02-13       Impact factor: 7.561

  7 in total

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