Literature DB >> 29924970

Defens-IN! Human α-Defensin 5 Acts as an Unwitting Double Agent to Promote Shigella Infection.

Alison G Murphy1, Kevin J Maloy2.   

Abstract

Shigella pathogenesis has confounded researchers for years because of its narrow host selectivity and extraordinary infectious capability. In this issue of Immunity, Xu et al. (2018) identify a cunning mechanism whereby Shigella hijacks human α-defensin 5 to enhance its adhesion and subsequent invasion.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID: 29924970     DOI: 10.1016/j.immuni.2018.05.015

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  2 in total

Review 1.  Defensins: A Double-Edged Sword in Host Immunity.

Authors:  Dan Xu; Wuyuan Lu
Journal:  Front Immunol       Date:  2020-05-07       Impact factor: 7.561

2.  An engineering probiotic producing defensin-5 ameliorating dextran sodium sulfate-induced mice colitis via Inhibiting NF-kB pathway.

Authors:  Lishan Zeng; Jiasheng Tan; Meng Xue; Le Liu; Mingming Wang; Liping Liang; Jun Deng; Wei Chen; Ye Chen
Journal:  J Transl Med       Date:  2020-03-02       Impact factor: 5.531

  2 in total

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