Literature DB >> 2992474

Mg2+ efflux is accomplished by an amiloride-sensitive Na+/Mg2+ antiport.

T Günther, J Vormann.   

Abstract

Mg2+ efflux from Mg2+-preloaded chicken erythrocytes is caused by an electroneutral Na+/Mg2+ antiport. It depends specifically on extracellular Na+, according to Michaelis-Menten kinetics (Km = 25 mM), and is reversibly noncompetitively inhibited by amiloride (Ki = 0.59 mM). In contrast to Na+/H+ antiport, Li+, Ca2+ and N-ethylmaleimide do not interfere with Na+/Mg2+ antiport. The Na+/Mg2+ antiport is driven by the intracellular/extracellular Mg2+ gradient.

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Year:  1985        PMID： 2992474     DOI： 10.1016/0006-291x(85)90450-4

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  18 in total

1.  Magnesium transport in ferret red cells.

Authors:  P W Flatman; L M Smith
Journal:  J Physiol       Date:  1990-12       Impact factor: 5.182

Review 2.  [Mg(2+) transport in the heart. An overview].

Authors:  H Ebel
Journal:  Herz       Date:  1997-06       Impact factor: 1.443

3.  Some properties of a system for sodium-dependent outward movement of magnesium from metabolizing human red blood cells.

Authors:  H Lüdi; H J Schatzmann
Journal:  J Physiol       Date:  1987-09       Impact factor: 5.182

4.  Demonstration of a Na+: Mg2+ exchange in human red cells by its sensitivity to tricyclic antidepressant drugs.

Authors:  J C Féray; R Garay
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1988-09       Impact factor: 3.000

5.  Modulation of Na+/Mg²+ exchanger stoichiometry ratio by Cl⁻ ions in basolateral rat liver plasma membrane vesicles.

Authors:  C Cefaratti; A Romani
Journal:  Mol Cell Biochem       Date:  2011-01-14       Impact factor: 3.396

Review 6.  Cellular magnesium homeostasis.

Authors:  Andrea M P Romani
Journal:  Arch Biochem Biophys       Date:  2011-05-27       Impact factor: 4.013

7.  KB-R7943 inhibits Na+-dependent Mg2+ efflux in rat ventricular myocytes.

Authors:  Michiko Tashiro; Hana Inoue; Masato Konishi
Journal:  J Physiol Sci       Date:  2010-09-23       Impact factor: 2.781

8.  Involvement of ERK1/2 and p38 in Mg2+ accumulation in liver cells.

Authors:  Lisa M Torres; Christie Cefaratti; Beverly Perry; Andrea Romani
Journal:  Mol Cell Biochem       Date:  2006-05-02       Impact factor: 3.396

9.  Free magnesium concentration in salamander photoreceptor outer segments.

Authors:  Chunhe Chen; Kei Nakatani; Yiannis Koutalos
Journal:  J Physiol       Date:  2003-09-18       Impact factor: 5.182

10.  Magnesium transport in magnesium-loaded ferret red blood cells.

Authors:  P W Flatman; L M Smith
Journal:  Pflugers Arch       Date:  1996-10       Impact factor: 3.657
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