Literature DB >> 2992430

Adsorption of human salivary mucins to hydroxyapatite.

L A Tabak, M J Levine, N K Jain, A R Bryan, R E Cohen, L D Monte, S Zawacki, G H Nancollas, A Slomiany, B L Slomiany.   

Abstract

The interactions between low (MG2) and high (MG1) molecular-weight human submandibular-sublingual mucin and hydroxyapatite (OHAp) were compared using a quantitative assay. Data obtained appeared to empirically fit the Langmuir adsorption isotherm. Apparent affinity constants derived from this isotherm indicated that MG1 had a greater affinity for OHAp than did MG2. Inhibition studies revealed that salivary glycolipids inhibited the interaction of MG1 and OHAp without influencing MG2 adsorption. In contrast, MG2 adsorption to OHAp was markedly inhibited by cysteine-containing salivary phosphoprotein fractions. Collectively, the data indicate MG1 and MG2 differ in their interaction with OHAp.

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Year:  1985        PMID: 2992430     DOI: 10.1016/0003-9969(85)90070-6

Source DB:  PubMed          Journal:  Arch Oral Biol        ISSN: 0003-9969            Impact factor:   2.633


  10 in total

1.  Adherence of oral streptococci to salivary glycoproteins.

Authors:  P A Murray; A Prakobphol; T Lee; C I Hoover; S J Fisher
Journal:  Infect Immun       Date:  1992-01       Impact factor: 3.441

2.  Aggregation of oral bacteria by human salivary mucins in comparison to salivary and gastric mucins of animal origin.

Authors:  H M Koop; M Valentijn-Benz; A V Nieuw Amerongen; P A Roukema; J de Graaff
Journal:  Antonie Van Leeuwenhoek       Date:  1990-11       Impact factor: 2.271

3.  Lubrication of selected salivary molecules and artificial salivas.

Authors:  A Aguirre; B Mendoza; M S Reddy; F A Scannapieco; M J Levine; M N Hatton
Journal:  Dysphagia       Date:  1989       Impact factor: 3.438

4.  A human salivary protein which promotes adhesion of Streptococcus mutans serotype c strains to hydroxyapatite.

Authors:  E Kishimoto; D I Hay; R J Gibbons
Journal:  Infect Immun       Date:  1989-12       Impact factor: 3.441

5.  In-situ hybridization localized MUC7 mucin gene expression to the mucous acinar cells of human and MUC7-transgenic mouse salivary glands.

Authors:  S H Khan; A Aguirre; L A Bobek
Journal:  Glycoconj J       Date:  1998-12       Impact factor: 2.916

6.  Tissue-specific expression of human salivary mucin gene, MUC7, in transgenic mice.

Authors:  L A Bobek; H Li; N Rojstaczer; C Jones; K W Gross; M J Levine
Journal:  Transgenic Res       Date:  1998-05       Impact factor: 2.788

7.  Salivary mucin 19 glycoproteins: innate immune functions in Streptococcus mutans-induced caries in mice and evidence for expression in human saliva.

Authors:  David J Culp; Bently Robinson; Melanie N Cash; Indraneel Bhattacharyya; Carol Stewart; Giancarlo Cuadra-Saenz
Journal:  J Biol Chem       Date:  2014-12-15       Impact factor: 5.157

8.  Analysis of Candida albicans adhesion to salivary mucin.

Authors:  M P Hoffman; C G Haidaris
Journal:  Infect Immun       Date:  1993-05       Impact factor: 3.441

9.  Structural features of the low-molecular-mass human salivary mucin.

Authors:  M S Reddy; L A Bobek; G G Haraszthy; A R Biesbrock; M J Levine
Journal:  Biochem J       Date:  1992-10-15       Impact factor: 3.857

10.  Identification and characterization of a Candida albicans-binding proteoglycan secreted from rat submandibular salivary glands.

Authors:  M P Hoffman; C G Haidaris
Journal:  Infect Immun       Date:  1994-03       Impact factor: 3.441

  10 in total

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