Literature DB >> 29923370

Immunotherapy for osteosarcoma: Where do we go from here?

Mary F Wedekind1,2, Lars M Wagner3, Timothy P Cripe1,2.   

Abstract

Osteosarcoma is the most common bone tumor in children and young adults, with few advances in survival and treatment, especially for metastatic disease, in the last 30 years. Recently, immunotherapy has begun to show promise in various adult cancers, but the utility of this approach for osteosarcoma remains relatively unexplored. In this review, we outline the mechanisms and status of immunotherapies currently in clinical trials as well as future therapies on the horizon, and discuss their potential application for osteosarcoma.
© 2018 The Authors. Pediatric Blood & Cancer Published by Wiley Periodicals, Inc.

Entities:  

Keywords:  immunotherapy; osteosarcoma; sarcoma

Mesh：

Substances：

Year:  2018        PMID： 29923370     DOI： 10.1002/pbc.27227

Source DB:  PubMed          Journal:  Pediatr Blood Cancer        ISSN： 1545-5009            Impact factor:   3.167


  42 in total

1.  Immune pathways and TP53 missense mutations are associated with longer survival in canine osteosarcoma.

Authors:  Sunetra Das; Rupa Idate; Daniel P Regan; Jared S Fowles; Susan E Lana; Douglas H Thamm; Daniel L Gustafson; Dawn L Duval
Journal:  Commun Biol       Date:  2021-10-11

2.  In vitro selection of DNA aptamers against human osteosarcoma.

Authors:  Khaliunsarnai Tsogtbaatar; Diana A Sousa; Debora Ferreira; Atakan Tevlek; Halil Murat Aydın; Eda Çelik; Ligia Rodrigues
Journal:  Invest New Drugs       Date:  2021-08-12       Impact factor: 3.850

Review 3.  Pharmaceutical Values of Calycosin: One Type of Flavonoid Isolated from Astragalus.

Authors:  Guowei Gong; Yuzhong Zheng; Yang Yang; Yixuan Sui; Zhen Wen
Journal:  Evid Based Complement Alternat Med       Date:  2021-05-06       Impact factor: 2.629

Review 4.  Osteosarcoma: a review of current and future therapeutic approaches.

Authors:  Xin Zhao; Qirui Wu; Xiuqing Gong; Jinfeng Liu; Yujie Ma
Journal:  Biomed Eng Online       Date:  2021-03-02       Impact factor: 2.819

Review 5.  Tissue engineered platforms for studying primary and metastatic neoplasm behavior in bone.

Authors:  Victoria L Thai; Katherine H Griffin; Steven W Thorpe; R Lor Randall; J Kent Leach
Journal:  J Biomech       Date:  2020-12-30       Impact factor: 2.712

6.  Development of a Machine Learning-Based Autophagy-Related lncRNA Signature to Improve Prognosis Prediction in Osteosarcoma Patients.

Authors:  Guang-Zhi Zhang; Zuo-Long Wu; Chun-Ying Li; En-Hui Ren; Wen-Hua Yuan; Ya-Jun Deng; Qi-Qi Xie
Journal:  Front Mol Biosci       Date:  2021-05-21

7.  Novel Human Antibodies to Insulin Growth Factor 2 Receptor (IGF2R) for Radioimmunoimaging and Therapy of Canine and Human Osteosarcoma.

Authors:  Jaline Broqueza; Chandra B Prabaharan; Samitha Andrahennadi; Kevin J H Allen; Ryan Dickinson; Valerie MacDonald-Dickinson; Ekaterina Dadachova; Maruti Uppalapati
Journal:  Cancers (Basel)       Date:  2021-05-04       Impact factor: 6.639

8.  Endogenous retrovirus envelope as a tumor-associated immunotherapeutic target in murine osteosarcoma.

Authors:  Mary Frances Wedekind; Katherine E Miller; Chun-Yu Chen; Pin-Yi Wang; Brian J Hutzen; Mark A Currier; Brooke Nartker; Ryan D Roberts; Louis Boon; Joe Conner; Stephanie LaHaye; Benjamin J Kelly; David Gordon; Peter White; Elaine R Mardis; Timothy P Cripe
Journal:  iScience       Date:  2021-06-19

Review 9.  Metabolic landscapes in sarcomas.

Authors:  Richard Miallot; Franck Galland; Virginie Millet; Jean-Yves Blay; Philippe Naquet
Journal:  J Hematol Oncol       Date:  2021-07-22       Impact factor: 17.388

10.  Charting a path for prioritization of novel agents for clinical trials in osteosarcoma: A report from the Children's Oncology Group New Agents for Osteosarcoma Task Force.

Authors:  Sarah B Whittle; Katharine Offer; Ryan D Roberts; Amy LeBlanc; Cheryl London; Robbie G Majzner; Alex Y Huang; Peter Houghton; E Alejandro Sweet Cordero; Patrick J Grohar; Michael Isakoff; Michael W Bishop; Elizabeth Stewart; Emily K Slotkin; Emily Greengard; Scott C Borinstein; Fariba Navid; Richard Gorlick; Katherine A Janeway; Damon R Reed; Pooja Hingorani
Journal:  Pediatr Blood Cancer       Date:  2021-06-16       Impact factor: 3.838
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