E Brenaut1, J A Halvorsen2, F J Dalgard3,4, L Lien4, F Balieva5, F Sampogna6, D Linder7, A W M Evers8, G B E Jemec9, U Gieler10, J Szepietowski11, F Poot12, I K Altunay13, A Y Finlay14, S S Salek15, C Szabo16, A Lvov17, S E Marron18, L Tomas-Aragones19, J Kupfer20, L Misery1. 1. Department of Dermatology, University Hospital, Brest, France. 2. Department of Dermatology, Oslo University Hospital, Oslo University, Oslo, Norway. 3. Department of Dermatology and Venereology, Skåne University Hospital, Lund University, Malmö, Sweden. 4. National Centre for Dual Diagnosis, Innlandet Hospital Trust, Brumunddal, Norway. 5. Department of Dermatology, Stavanger University Hospital, Stavanger, Norway. 6. Clinical Epidemiology Unit, Istituto Dermopatico dell'Immacolata (IDI)- IRCCS FLMM, Rome, Italy. 7. Section of Biostatistics, University of Oslo, Oslo, Norway. 8. Department of Health, Medicine and Neuropsychology, Leiden University, Leiden, The Netherlands. 9. Department of Dermatology, Zealand University Hospital, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. 10. Department of Dermatology, Justus Liebig University, Giessen, Germany. 11. Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland. 12. Department of Dermatology, Universite Libre de Bruxelles, Brussels, Belgium. 13. Dermatology and Veneteology Clinic, Şişli Hamidiye Etfal Training and Research Center, University of Health Science, Istanbul, Turkey. 14. Department of Dermatology, Cardiff University School of Medicine, Cardiff, UK. 15. School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK. 16. Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary. 17. Moscow Scientific and Practical Centre of Dermatovenereology and Cosmetology, Moscow, Russia. 18. Department of Dermatology, Royo Villanova Hospital, Zaragoza, Spain. 19. Department of Psychology, University of Zaragoza, Zaragoza, Spain. 20. Institute of Medical Psychology, Justus Liebig University, Giessen, Germany.
Abstract
BACKGROUND: Prurigo is defined by the presence of chronic pruritus and multiple localized or generalized pruriginous lesions. OBJECTIVE: The aim of this study was to assess the psychological burden of prurigo in patients of European countries. METHODS: In this multicentre European study, 3635 general dermatology outpatients and 1359 controls were included. Socio-demographic data and answers to questionnaires (regarding quality of life, general health, anxiety and depression and suicidal ideation) were collected. RESULTS: There were 27 patients with prurigo; of these, 63% were men, and the mean age was 58.6 years. Among patients with prurigo, 10 of 27 (37%) suffered from anxiety and 8 of 27 (29%) from depression. Suicidal ideation was reported in 5 of 27 (19%) patients, and for four of these five patients, suicidal ideation was related to their skin disease. These frequencies were higher in the 10 commonest dermatological diseases (including psoriasis, atopic dermatitis and leg ulcers). The impact on quality of life was severe, with a mean Dermatologic Life Quality Index (DLQI) of 12.4, with an extreme impact on quality of life for 23% of patients and a very large impact for 27% of patients. CONCLUSION: The psychological comorbidities of prurigo are common, greater than those of other skin diseases, and their impact on quality of life is significant. Thus, it is important to study this condition and to find new treatments.
BACKGROUND:Prurigo is defined by the presence of chronic pruritus and multiple localized or generalized pruriginous lesions. OBJECTIVE: The aim of this study was to assess the psychological burden of prurigo in patients of European countries. METHODS: In this multicentre European study, 3635 general dermatology outpatients and 1359 controls were included. Socio-demographic data and answers to questionnaires (regarding quality of life, general health, anxiety and depression and suicidal ideation) were collected. RESULTS: There were 27 patients with prurigo; of these, 63% were men, and the mean age was 58.6 years. Among patients with prurigo, 10 of 27 (37%) suffered from anxiety and 8 of 27 (29%) from depression. Suicidal ideation was reported in 5 of 27 (19%) patients, and for four of these five patients, suicidal ideation was related to their skin disease. These frequencies were higher in the 10 commonest dermatological diseases (including psoriasis, atopic dermatitis and leg ulcers). The impact on quality of life was severe, with a mean Dermatologic Life Quality Index (DLQI) of 12.4, with an extreme impact on quality of life for 23% of patients and a very large impact for 27% of patients. CONCLUSION: The psychological comorbidities of prurigo are common, greater than those of other skin diseases, and their impact on quality of life is significant. Thus, it is important to study this condition and to find new treatments.
Authors: Manuel P Pereira; Claudia Zeidler; Joanna Wallengren; Jon Anders Halvorsen; Elke Weisshaar; Simone Garcovich; Laurent Misery; Emilie Brenaut; Ekin Şavk; Nikolay Potekaev; Andrey Lvov; Svetlana Bobko; Jacek C Szepietowski; Adam Reich; Agnieszka Bozek; Franz J Legat; Martin Metz; Markus Streit; Esther Serra-Baldrich; Margarida Gonçalo; Michael Storck; Teresa Nau; Vincent Hoffmann; Sabine Steinke; Ina Greiwe; Martin Dugas; Matthias Augustin; Sonja Ständer Journal: Acta Derm Venereol Date: 2021-02-17 Impact factor: 3.875