Literature DB >> 29923000

Effects of Thermoextracts of Brucella S and L Forms on Lipid Peroxidation and Antioxidant Defense in Organs of Laboratory Animals.

V I Dubrovina1, S V Balakhonov2, O V Yurieva2, T P Starovoitova2, N L Barannikova2, L E Tokareva2, A B Pyatidesyatnikova2, K Yu Yastremskaya2, T T Shkaruba2.   

Abstract

The dynamics of LPO marker malondialdehyde formation and peroxidase-destroying activity was studied in homogenized organs of guinea pigs, immunized with thermoextracts from S and L forms Brucella abortus I-206. The L form brucella thermoextract exhibited a lower reactogenicity and adequately activated the antioxidant system, due to which the destructive effects of ROS could be partially neutralized during the vaccinal process.

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Keywords:  antioxidant status; immunization; lipid peroxidation; oxidative stress

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Year:  2018        PMID： 29923000     DOI： 10.1007/s10517-018-4138-2

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  1 in total

1.  Reparative and Immunomodulatory Potential of Low-Molecular-Weight Fractions of Secondary Metabolites of Bacillus sp.

Authors:  L F Kalenova; S A Petrov; Yu G Sukhovei
Journal:  Bull Exp Biol Med       Date:  2022-01-10       Impact factor: 0.804
  1 in total

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