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Literature DB >> 29922908

Application of pharmacogenetics in clinical practice: problems and solutions.

Abstract

This paper discusses difficulties of pharmacogenomic data integration into clinical practice. It emphasizes the need for developing simple and easy to use bioinformatics tools to help prescribers to rapidly access and use genetic data in clinical decision-making at the point of encounter.

Keywords: Clinical informatics tools; Drug–drug interactions; Drug–gene interactions; Medication side effect estimation

Mesh：

Substances：

Year: 2018 PMID： 29922908 DOI： 10.1007/s00702-018-1894-0

Source DB: PubMed Journal: J Neural Transm (Vienna) ISSN： 0300-9564 Impact factor: 3.575

26 in total

Review 1. Cytochrome P450 variations in different ethnic populations.

Authors: Joseph McGraw; Donald Waller
Journal: Expert Opin Drug Metab Toxicol Date: 2012-01-31 Impact factor: 4.481

Review 2. Cytochrome P450 Structure, Function and Clinical Significance: A Review.

Authors: Palrasu Manikandan; Siddavaram Nagini
Journal: Curr Drug Targets Date: 2018 Impact factor: 3.465

3. Implementation of a pharmacogenomics service in a community pharmacy.

Authors: Stefanie P Ferreri; Angelo J Greco; Natasha M Michaels; Shanna K O'Connor; Rebecca W Chater; Anthony J Viera; Hawazin Faruki; Howard L McLeod; Mary W Roederer
Journal: J Am Pharm Assoc (2003) Date: 2014 Mar-Apr

Review 4. Impact of physiological, pathological and environmental factors on the expression and activity of human cytochrome P450 2D6 and implications in precision medicine.

Authors: Zhi-Xu He; Xiao-Wu Chen; Zhi-Wei Zhou; Shu-Feng Zhou
Journal: Drug Metab Rev Date: 2015-11-16 Impact factor: 4.518

5. Human genetic variation of CYP450 superfamily: analysis of functional diversity in worldwide populations.

Authors: Renato Polimanti; Sara Piacentini; Dario Manfellotto; Maria Fuciarelli
Journal: Pharmacogenomics Date: 2012-12 Impact factor: 2.533

6. Pharmacogenetics for Safe Codeine Use in Sickle Cell Disease.

Authors: Roseann S Gammal; Kristine R Crews; Cyrine E Haidar; James M Hoffman; Donald K Baker; Patricia J Barker; Jeremie H Estepp; Deqing Pei; Ulrich Broeckel; Winfred Wang; Mitchell J Weiss; Mary V Relling; Jane Hankins
Journal: Pediatrics Date: 2016-07 Impact factor: 7.124

Review 7. Stakeholder views on pharmacogenomic testing.

Authors: Haridarshan N Patel; Iulia D Ursan; Patrick M Zueger; Larisa H Cavallari; A Simon Pickard
Journal: Pharmacotherapy Date: 2013-10-24 Impact factor: 4.705

Review 8. Integrating clinical decision support systems for pharmacogenomic testing into clinical routine - a scoping review of designs of user-system interactions in recent system development.

Authors: Marc Hinderer; Martin Boeker; Sebastian A Wagner; Martin Lablans; Stephanie Newe; Jan L Hülsemann; Michael Neumaier; Harald Binder; Harald Renz; Till Acker; Hans-Ulrich Prokosch; Martin Sedlmayr
Journal: BMC Med Inform Decis Mak Date: 2017-06-06 Impact factor: 2.796