| Literature DB >> 29921469 |
Geoffroy de Faudeur1, Bas Brouwers2, Frans Schuit3, John W M Creemers4, Bruno Ramos-Molina5.
Abstract
The minigene encoding human growth hormone (hGH) has been incorporated into over 300 transgenic mouse lines to improve transgene expression. However, unexpected and functional hGH expression can drastically alter physiology. We list here the mouse lines in which ectopic hGH has been confirmed, and we provide a wiki for lines awaiting analysis.Entities:
Keywords: Cre-loxP; human growth hormone; prolactin receptor; transgenic mice
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Year: 2018 PMID： 29921469 DOI： 10.1016/j.tem.2018.05.005
Source DB: PubMed Journal: Trends Endocrinol Metab ISSN： 1043-2760 Impact factor: 12.015