Literature DB >> 2992121

Changes in adrenal function as a possible mechanism for elevation of serum glucose by a single large dose of fluoride.

Y Suketa, Y Asao, Y Kanamoto, T Sakashita, S Okada.   

Abstract

Serum glucose was elevated immediately after ip administration of a single large dose of fluoride (NaF 35 mg/kg) to rats. Moreover, elevation of serum glucose following ip administration of 35 mg/kg of fluoride to rats was suppressed by adrenalectomy, dibenamine, or propranolol, but not by thyroid-parathyroidectomy. The elevation of serum glucose was associated with enhancement of glucose-6-phosphatase activities in liver and kidney in fluoride-treated rats.

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Year:  1985        PMID： 2992121     DOI： 10.1016/0041-008x(85)90076-6

Source DB:  PubMed          Journal:  Toxicol Appl Pharmacol        ISSN： 0041-008X            Impact factor:   4.219


  3 in total

1.  Reversible impairment of glucose tolerance in patients with endemic fluorosis. Fluoride Collaborative Study Group.

Authors:  N Trivedi; A Mithal; S K Gupta; M M Godbole
Journal:  Diabetologia       Date:  1993-09       Impact factor: 10.122

Review 2.  Fluoride Exposure Induces Inhibition of Sodium-and Potassium-Activated Adenosine Triphosphatase (Na+, K+-ATPase) Enzyme Activity: Molecular Mechanisms and Implications for Public Health.

Authors:  Declan Timothy Waugh
Journal:  Int J Environ Res Public Health       Date:  2019-04-21       Impact factor: 3.390

Review 3.  Fluoride Exposure Induces Inhibition of Sodium/Iodide Symporter (NIS) Contributing to Impaired Iodine Absorption and Iodine Deficiency: Molecular Mechanisms of Inhibition and Implications for Public Health.

Authors:  Declan Timothy Waugh
Journal:  Int J Environ Res Public Health       Date:  2019-03-26       Impact factor: 3.390
  3 in total

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