Seung-Hyun Boo1, Min Cheol Joo1, Jeong Mi Lee2, Seung Chan Kim3, Young Mi Yu1, Min-Su Kim4,5. 1. Department of Rehabilitation Medicine, Wonkwang University School of Medicine, Iksan, Republic of Korea. 2. Department of Preventive Medicine, Wonkwang University School of Medicine, Iksan, Republic of Korea. 3. Department of Statistics, Pukyong National University, Busan, Republic of Korea. 4. Department of Rehabilitation Medicine, Wonkwang University School of Medicine, Iksan, Republic of Korea. helmaine@naver.com. 5. Department of Rehabilitation Medicine, Wonkwang University Hospital at 895, Muwang-ro, Iksan-si, 54538, Republic of Korea. helmaine@naver.com.
Abstract
BACKGROUND: Sarcopenia reduces physical ability and cardiorespiratory fitness (CRF), leading to poor quality of life. AIM: The aim of this study was to investigate the relationship between skeletal muscle mass and CRF in elderly men. METHODS: We assessed 102 community-dwelling men over 60 years old. Appendicular skeletal muscle mass (ASM) was determined using bioelectrical impedance analysis, and the skeletal muscle mass index (SMI) was calculated as ASM divided by the square of height. Subjects with an SMI less than 7.0 kg/m2 were included in the sarcopenic group, as recommended by the Asian Working Group for Sarcopenia. To investigate CRF parameters, a cardiopulmonary exercise test was performed using the Bruce protocol. CRF parameters were subdivided into aerobic capacity, cardiovascular response, and ventilatory response. RESULTS: Of the 102 subjects, 15 (14.7%) were included in the sarcopenic group. There were significant correlations between SMI and peak oxygen consumption (VO2peak) (r = 0.597, p < 0.001), and between SMI and VO2peak/weight (r = 0.268, p = 0.024). Moreover, there were positive correlations between SMI and first ventilatory threshold (VT1) (r = 0.352, p = 0.008) and between SMI and VT1/weight (r = 0.189, p = 0.039). Additionally, peak oxygen pulse (O2pulsepeak) was significantly correlated with SMI (r = 0.558, p < 0.001). VO2peak, VO2peak/weight and O2pulsepeak showed significant differences between the sarcopenic and non-sarcopenic groups (p < 0.05, all). In multiple linear regression analyses, the factor related to VO2peak was SMI (β = 0.473, p < 0.001) and that related to O2pulsepeak was also SMI (β = 0.442, p < 0.001). DISCUSSION AND CONCLUSIONS: This study demonstrated that skeletal muscle mass might be closely associated with CRF. Therefore, sarcopenia should be appropriately managed to improve an individual's CRF.
BACKGROUND:Sarcopenia reduces physical ability and cardiorespiratory fitness (CRF), leading to poor quality of life. AIM: The aim of this study was to investigate the relationship between skeletal muscle mass and CRF in elderly men. METHODS: We assessed 102 community-dwelling men over 60 years old. Appendicular skeletal muscle mass (ASM) was determined using bioelectrical impedance analysis, and the skeletal muscle mass index (SMI) was calculated as ASM divided by the square of height. Subjects with an SMI less than 7.0 kg/m2 were included in the sarcopenic group, as recommended by the Asian Working Group for Sarcopenia. To investigate CRF parameters, a cardiopulmonary exercise test was performed using the Bruce protocol. CRF parameters were subdivided into aerobic capacity, cardiovascular response, and ventilatory response. RESULTS: Of the 102 subjects, 15 (14.7%) were included in the sarcopenic group. There were significant correlations between SMI and peak oxygen consumption (VO2peak) (r = 0.597, p < 0.001), and between SMI and VO2peak/weight (r = 0.268, p = 0.024). Moreover, there were positive correlations between SMI and first ventilatory threshold (VT1) (r = 0.352, p = 0.008) and between SMI and VT1/weight (r = 0.189, p = 0.039). Additionally, peak oxygen pulse (O2pulsepeak) was significantly correlated with SMI (r = 0.558, p < 0.001). VO2peak, VO2peak/weight and O2pulsepeak showed significant differences between the sarcopenic and non-sarcopenic groups (p < 0.05, all). In multiple linear regression analyses, the factor related to VO2peak was SMI (β = 0.473, p < 0.001) and that related to O2pulsepeak was also SMI (β = 0.442, p < 0.001). DISCUSSION AND CONCLUSIONS: This study demonstrated that skeletal muscle mass might be closely associated with CRF. Therefore, sarcopenia should be appropriately managed to improve an individual's CRF.
Authors: Tanvir S Sian; Thomas B Inns; Amanda Gates; Brett Doleman; Joseph J Bass; Philip J Atherton; Jonathan N Lund; Bethan E Phillips Journal: BMC Geriatr Date: 2022-06-28 Impact factor: 4.070
Authors: Annefleur E M Berkel; Laura van Wijk; David P J van Dijk; Sanne N Prins; Job van der Palen; Nico L U van Meeteren; Steven W M Olde Damink; Joost M Klaase; Bart C Bongers Journal: Colorectal Dis Date: 2021-10-20 Impact factor: 3.917
Authors: Hayley E Billingsley; Justin M Canada; Dave L Dixon; Danielle L Kirkman; Natalie Bohmke; Brando Rotelli; Dinesh Kadariya; Roshanak Markley; Benjamin W Van Tassell; Francesco S Celi; Antonio Abbate; Salvatore Carbone Journal: Int J Cardiol Date: 2022-03-09 Impact factor: 4.039