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Literature DB >> 2991597

Decreasing the number of 68-base-pair tandem repeats in the BK virus transcriptional control region reduces plaque size and enhances transforming capacity.

Abstract

Wild-type BK virus, which has three 68-base-pair (bp) elements tandemly repeated in its transcriptional control region, forms clear, large plaques in human embryonic kidney cell cultures but rarely transforms hamster or rat cells. From this BK virus DNA, deletion mutants with fewer than three 68-bp elements were constructed and characterized. The mutant DNA with two 68-bp elements formed small, turbid plaques in human cell cultures and transformed rat 3Y1 cells inefficiently. The mutant DNA with one 68-bp element formed minute, turbid plaques in human cell cultures and transformed rat cells efficiently.

Entities: Disease Species

Mesh：

Year: 1985 PMID： 2991597 PMCID： PMC255067

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

13 in total

1. Viable deletion mutant of human papovavirus BK that induces insulinomas in hamsters.

Authors: S Watanabe; K Yoshiike; A Nozawa; Y Yuasa; S Uchida
Journal: J Virol Date: 1979-12 Impact factor: 5.103

2. Selective extraction of polyoma DNA from infected mouse cell cultures.

Authors: B Hirt
Journal: J Mol Biol Date: 1967-06-14 Impact factor: 5.469

3. Enchancement of the infectivity of simian virus 40 deoxyribonucleic acid with diethylaminoethyl-dextran.

Authors: J H McCutchan; J S Pagano
Journal: J Natl Cancer Inst Date: 1968-08 Impact factor: 13.506

4. A new technique for the assay of infectivity of human adenovirus 5 DNA.

Authors: F L Graham; A J van der Eb
Journal: Virology Date: 1973-04 Impact factor: 3.616

5. The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element.

Authors: P Hearing; T Shenk
Journal: Cell Date: 1983-07 Impact factor: 41.582

6. BK virus DNA: complete nucleotide sequence of a human tumor virus.

Authors: R C Yang; R Wu
Journal: Science Date: 1979-10-26 Impact factor: 47.728

7. Definition of the simian virus 40 early promoter region and demonstration of a host range bias in the enhancement effect of the simian virus 40 72-base-pair repeat.

Authors: B J Byrne; M S Davis; J Yamaguchi; D J Bergsma; K N Subramanian
Journal: Proc Natl Acad Sci U S A Date: 1983-02 Impact factor: 11.205

7. Hybrid genomes of the polyomaviruses JC virus, BK virus, and simian virus 40: identification of sequences important for efficient transformation.

Authors: B Bollag; W F Chuke; R J Frisque
Journal: J Virol Date: 1989-02 Impact factor: 5.103

8. JC virus-simian virus 40 genomes containing heterologous regulatory signals and chimeric early regions: identification of regions restricting transformation by JC virus.

Authors: S Haggerty; D L Walker; R J Frisque
Journal: J Virol Date: 1989-05 Impact factor: 5.103

9. Identification of HeLa cell nuclear factors that bind to and activate the early promoter of human polyomavirus BK in vitro.

Authors: T Chakraborty; G C Das
Journal: Mol Cell Biol Date: 1989-09 Impact factor: 4.272

10. BK virus large T antigen: interactions with the retinoblastoma family of tumor suppressor proteins and effects on cellular growth control.

Authors: K F Harris; J B Christensen; M J Imperiale
Journal: J Virol Date: 1996-04 Impact factor: 5.103

Decreasing the number of 68-base-pair tandem repeats in the BK virus transcriptional control region reduces plaque size and enhances transforming capacity.

1. Viable deletion mutant of human papovavirus BK that induces insulinomas in hamsters.

2. Selective extraction of polyoma DNA from infected mouse cell cultures.

3. Enchancement of the infectivity of simian virus 40 deoxyribonucleic acid with diethylaminoethyl-dextran.

4. A new technique for the assay of infectivity of human adenovirus 5 DNA.

5. The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element.

6. BK virus DNA: complete nucleotide sequence of a human tumor virus.

7. Definition of the simian virus 40 early promoter region and demonstration of a host range bias in the enhancement effect of the simian virus 40 72-base-pair repeat.

8. Multiple point mutations affecting the simian virus 40 enhancer.

9. Tumorigenicity of human BK papovavirus plaque isolates, wild-type and plaque morphology mutant, in hamsters.

10. Expression of viral early functions in rat 3Y1 cells infected with human papovavirus BK.

1. Nucleotide sequence of the human polyomavirus AS virus, an antigenic variant of BK virus.

Review 2. The multiple codes of nucleotide sequences.

3. Complex functional interactions at the early enhancer of the PQ strain of BK virus.

4. Regulatory DNA sequence conserved in the course of BK virus evolution.

5. Evolutionary changes of transcriptional control region in a minute-plaque viable deletion mutant of BK virus.

6. Molecular and biological properties of BK virus-IR, a BK virus variant isolated from a human tumor.

7. Hybrid genomes of the polyomaviruses JC virus, BK virus, and simian virus 40: identification of sequences important for efficient transformation.

8. JC virus-simian virus 40 genomes containing heterologous regulatory signals and chimeric early regions: identification of regions restricting transformation by JC virus.

9. Identification of HeLa cell nuclear factors that bind to and activate the early promoter of human polyomavirus BK in vitro.

10. BK virus large T antigen: interactions with the retinoblastoma family of tumor suppressor proteins and effects on cellular growth control.