Literature DB >> 29915870

A systematic review of clinical pharmacist interventions in paediatric hospital patients.

Aaron Drovandi1, Kelvin Robertson2, Matthew Tucker2, Niechole Robinson2, Stephen Perks2, Therése Kairuz3.   

Abstract

Clinical pharmacists provide beneficial services to adult patients, though their benefits for paediatric hospital patients are less defined. Five databases were searched using the MeSH terms 'clinical pharmacist', 'paediatric/paediatric', 'hospital', and 'intervention' for studies with paediatric patients conducted in hospital settings, and described pharmacist-initiated interventions, published between January 2000 and October 2017. The search strategy after full-text review identified 12 articles matching the eligibility criteria. Quality appraisal checklists from the Joanna Briggs Institute were used to appraise the eligible articles. Clinical pharmacist services had a positive impact on paediatric patient care. Medication errors intercepted by pharmacists included over- and under-dosing, missed doses, medication history gaps, allergies, and near-misses. Interventions to address these errors were positively received, and implemented by physicians, with an average acceptance rate of over 95%. Clinical pharmacist-initiated education resulted in improved medication understanding and adherence, improved patient satisfaction, and control of chronic medical conditions.
Conclusion: This review found that clinical pharmacists in paediatric wards may reduce drug-related problems and improve patient outcomes. The benefits of pharmacist involvement appear greatest when directly involved in ward rounds, due to being able to more rapidly identify medication errors during the prescribing phase, and provide real-time advice and recommendations to prescribers. What is Known: • Complex paediatric conditions can require multiple pharmaceutical treatments, utilised in a safe manner to ensure good patient outcomes • The benefits of pharmacist interventions when using these treatments are well-documented in adult patients, though less so in paediatric patients What is New: • Pharmacists are adept at identifying and managing medication errors for paediatric patients, including incorrect doses, missed doses, and gaps in medication history • Interventions recommended by pharmacists are generally well-accepted by prescribing physicians, especially when recommendations can be made during the prescribing phase of treatment.

Entities:  

Keywords:  Clinical pharmacist; Medication dosing; Medication reconciliation; Patient safety; Prescribing errors

Mesh:

Year:  2018        PMID: 29915870     DOI: 10.1007/s00431-018-3187-x

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  34 in total

1.  Pediatric drug-related problems: a multicenter study in four French-speaking countries.

Authors:  Sonia Prot-Labarthe; Ermindo R Di Paolo; Annie Lavoie; Stefanie Quennery; Jean-François Bussières; Françoise Brion; Olivier Bourdon
Journal:  Int J Clin Pharm       Date:  2012-12-22

Review 2.  Clinical pharmacists and inpatient medical care: a systematic review.

Authors:  Peter J Kaboli; Angela B Hoth; Brad J McClimon; Jeffrey L Schnipper
Journal:  Arch Intern Med       Date:  2006-05-08

Review 3.  Hospital-based medication reconciliation practices: a systematic review.

Authors:  Stephanie K Mueller; Kelly Cunningham Sponsler; Sunil Kripalani; Jeffrey L Schnipper
Journal:  Arch Intern Med       Date:  2012-07-23

Review 4.  Paediatric pharmacokinetics: key considerations.

Authors:  Hannah Katharine Batchelor; John Francis Marriott
Journal:  Br J Clin Pharmacol       Date:  2015-03       Impact factor: 4.335

5.  Impact of an emergency department pharmacy on medication omission and delay.

Authors:  Greg P Marconi; Ilene Claudius
Journal:  Pediatr Emerg Care       Date:  2012-01       Impact factor: 1.454

Review 6.  Systematic review of medication errors in pediatric patients.

Authors:  Maisoon Abdullah Ghaleb; Nick Barber; Bryony D Franklin; Vincent W S Yeung; Zahra F Khaki; Ian C K Wong
Journal:  Ann Pharmacother       Date:  2006-09-19       Impact factor: 3.154

7.  ASHP national survey of pharmacy practice in hospital settings: prescribing and transcribing--2001.

Authors:  C A Pedersen; P J Schneider; J P Santell
Journal:  Am J Health Syst Pharm       Date:  2001-12-01       Impact factor: 2.637

8.  Clinical activities of an academic pediatric pharmacy team.

Authors:  Michelle E Condren; Mark R Haase; Sherry A Luedtke; Allyson S Gaylor
Journal:  Ann Pharmacother       Date:  2004-02-06       Impact factor: 3.154

Review 9.  Incidence and nature of dosing errors in paediatric medications: a systematic review.

Authors:  Ian C K Wong; Maisoon A Ghaleb; Bryony D Franklin; Nick Barber
Journal:  Drug Saf       Date:  2004       Impact factor: 5.606

Review 10.  Medication reconciliation during transitions of care as a patient safety strategy: a systematic review.

Authors:  Janice L Kwan; Lisha Lo; Margaret Sampson; Kaveh G Shojania
Journal:  Ann Intern Med       Date:  2013-03-05       Impact factor: 25.391

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  10 in total

1.  Interventions to Reduce Pediatric Prescribing Errors in Professional Healthcare Settings: A Systematic Review of the Last Decade.

Authors:  Joachim A Koeck; Nicola J Young; Udo Kontny; Thorsten Orlikowsky; Dirk Bassler; Albrecht Eisert
Journal:  Paediatr Drugs       Date:  2021-05-07       Impact factor: 3.022

Review 2.  Lymphatic Abnormalities in Noonan Syndrome Spectrum Disorders: A Systematic Review.

Authors:  Julia Sleutjes; Lotte Kleimeier; Erika Leenders; Willemijn Klein; Jos Draaisma
Journal:  Mol Syndromol       Date:  2021-09-10

Review 3.  Factors influencing the implementation of clinical pharmacy services on paediatric patient care in hospital settings.

Authors:  Conor Ming-Ho Sin; Chi Huynh; Dania Dahmash; Ian D Maidment
Journal:  Eur J Hosp Pharm       Date:  2021-01-20

4.  Predicting the risk of drug-drug interactions in psychiatric hospitals: a retrospective longitudinal pharmacovigilance study.

Authors:  Jan Wolff; Gudrun Hefner; Claus Normann; Klaus Kaier; Harald Binder; Katharina Domschke; Christoph Hiemke; Michael Marschollek; Ansgar Klimke
Journal:  BMJ Open       Date:  2021-04-09       Impact factor: 2.692

5.  A cost-benefit analysis of hospital-wide medication reviews: a period prevalence study.

Authors:  Sarah Wilkes; Rianne J Zaal; Alan Abdulla; Nicole G M Hunfeld
Journal:  Int J Clin Pharm       Date:  2021-09-08

6.  Implementation of virtual clinical pharmacy services by incorporating medical professionals and pharmacy students: A novel patient-oriented system to advance healthcare in India.

Authors:  Mohammed Salim Karattuthodi; Shabeer Ali Thorakkattil; Ajmal Karumbaru Kuzhiyil; Dilip Chandrasekhar; Khyathi N Bhojak
Journal:  Explor Res Clin Soc Pharm       Date:  2022-03-17

7.  The Impact of Clinical Pharmacy Services in a Tertiary Care Center Specialized in Pediatric Hemato-Oncology.

Authors:  Christina Gradwohl; Gernot Engstler; Martina Anditsch; Herbert Pichler; Gunar Stemer
Journal:  Children (Basel)       Date:  2022-03-31

Review 8.  An overview on the treatment and outcome factors of ankle fractures in elderly men and women aged 80 and over: a systematic review.

Authors:  Marieke S van Halsema; Rick A R Boers; Vincent J M Leferink
Journal:  Arch Orthop Trauma Surg       Date:  2021-09-21       Impact factor: 2.928

9.  Medication follow-up in newborns with extremely low birth-weight.

Authors:  Catarine V Loureiro; Marta M Fonteles; Mylenne B Mascarenhas; Elana F Chaves; Paulo Y Firmino
Journal:  Pharm Pract (Granada)       Date:  2019-11-20

10.  The "Warrior" system: a new useful emergency simulator to train clinical pharmacists in emergency medicine.

Authors:  Cong Huang; Yang-Yang Wang; Jing-Jie Zhou; Yan-Fei Liu; Xin He
Journal:  Medicine (Baltimore)       Date:  2020-05-29       Impact factor: 1.817

  10 in total

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