Literature DB >> 29915822

Novel hemagglutinin-binding sulfated oligofucosides and their effect on influenza virus infection.

Shuhei Kosono1, Akihiro Kasai1, Sumika Komaba1, Teruhiko Matsubara2, Toshinori Sato2, Daisuke Takahashi1, Kazunobu Toshima1.   

Abstract

Among a series of chemically synthesized fucoidan derivatives (1-9), 5 was found for the first time to bind to influenza virus hemagglutinins (HAs) and inhibit hemagglutination activity. In addition, a designed C3-symmetric tripodal ligand 10, synthesized with three sulfated oligofucoside moieties of 5, exhibited much greater hemagglutination inhibition activity than 5. A plaque assay using MDCK cells demonstrated that 10 effectively inhibited influenza virus infection.

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Year:  2018        PMID： 29915822     DOI： 10.1039/c8cc03865a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

1.  Synthesis of low-molecular weight fucoidan derivatives and their binding abilities to SARS-CoV-2 spike proteins.

Authors:  Tatsuki Koike; Aoi Sugimoto; Shuhei Kosono; Sumika Komaba; Yuko Kanno; Takashi Kitamura; Itsuki Anzai; Tokiko Watanabe; Daisuke Takahashi; Kazunobu Toshima
Journal:  RSC Med Chem       Date:  2021-09-07

Review 2.  Therapies from Fucoidan: New Developments.

Authors:  Helen J Fitton; Damien S Stringer; Ah Young Park; Samuel N Karpiniec
Journal:  Mar Drugs       Date:  2019-10-09       Impact factor: 5.118

Review 3.  Recent progress in chemical approaches for the development of novel neuraminidase inhibitors.

Authors:  Ahmed Mahal; Meitao Duan; Dhafer S Zinad; Ranjan K Mohapatra; Ahmad J Obaidullah; Xiaoyi Wei; Manoj K Pradhan; Debadutta Das; Venkataramana Kandi; Hany S Zinad; Quanhong Zhu
Journal:  RSC Adv       Date:  2021-01-06       Impact factor: 3.361

Review 4.  Heparan Sulfate and Sialic Acid in Viral Attachment: Two Sides of the Same Coin?

Authors:  Ivan Emmanuel Ramos-Martínez; Edgar Ramos-Martínez; René Álvaro Segura-Velázquez; Manuel Saavedra-Montañez; Jacquelynne Brenda Cervantes-Torres; Marco Cerbón; Dulce Papy-Garcia; Edgar Zenteno; José Ivan Sánchez-Betancourt
Journal:  Int J Mol Sci       Date:  2022-08-30       Impact factor: 6.208

5.  Antiviral Activities of Compounds Isolated from Pinus densiflora (Pine Tree) against the Influenza A Virus.

Authors:  Thi Kim Quy Ha; Ba Wool Lee; Ngoc Hieu Nguyen; Hyo Moon Cho; Thamizhiniyan Venkatesan; Thi Phuong Doan; Eunhee Kim; Won Keun Oh
Journal:  Biomolecules       Date:  2020-05-04
  5 in total

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