Literature DB >> 29913520

Subependymomas - Characteristics of a "Leave me Alone" Lesion.

Sara Kammerer1, Monika Mueller-Eschner1, Arne Lauer1, Anna-Luisa Luger2, Johanna Quick-Weller3, Kea Franz3, Patrick Harter4, Joachim Berkefeld1, Marlies Wagner1.   

Abstract

PURPOSE: Intracranial subependymomas are rare, mostly asymptomatic tumours, which are often found incidentally and therefore did not receive much attention in previous literature. By being classified as benign grade I in the WHO classification of tumours of the central nervous system, they are given a special status compared to the other ependymal tumours. Tumor recurrences are a rarity, spinal "drop metastases" do not occur. While etiological, pathological and therapeutic characteristics have been subject of several publications over the last few decades and have meanwhile been well studied, the imaging characteristics are much less well received. MATERIAL AND
METHOD: Retrospective analysis of our relatively large group of 33 patients with subependymoma, including 4 patients with a mixture of subependymomas with ependymal cell fractions in terms of imaging and clinical aspects and with reference to a current literature review.
RESULTS: Subependymomas have typical image morphologic characteristics that differentiate them from tumors of other entities, however, the rare subgroup of histopathological mixtures of subependymomas with ependymal cell fractions has no distinctly different imaging properties.
CONCLUSIONS: Knowing the imaging characteristics of subpendymoma and their differential diagnoses is of particular importance in order to be able to decide between the necessity of follow-up controls, an early invasive diagnosis or, depending on the entity, tumor resection. KEY POINTS: · Subependymomas have typical imaging characteristics that are clearly distinguishable from other entities.. · Increased incidence in middle/ older aged men, most frequent localization: 4th ventricle.. · Symptomatic subependymomas, often located in lateral ventricles, are usually characterized by hydrocephalus.. · Radiological identification of mixed subependymoma with ependymal cell fractions is not possible.. · Image based differentiation from other entities is important for the procedure.. CITATION FORMAT: · Kammerer S, Mueller-Eschner M, Lauer A et al. Subependymomas - Characteristics of a "Leave me Alone" Lesion. Fortschr Röntgenstr 2018; 190: 955 - 966. © Georg Thieme Verlag KG Stuttgart · New York.

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Year:  2018        PMID: 29913520     DOI: 10.1055/a-0576-1028

Source DB:  PubMed          Journal:  Rofo        ISSN: 1438-9010


  3 in total

1.  Intraparenchymal subependymoma: Case report and literature review.

Authors:  Othavio Gomes Lopes; Felipe Calmon Du Pin Almeida; Gustavo Augusto Porto Sereno Cabral; Rodrigo Dias Guimaraes; Ruy Castro Monteiro da Silva Filho; Jose Alberto Landeiro
Journal:  Surg Neurol Int       Date:  2021-04-14

Review 2.  Imaging characteristics of 4th ventricle subependymoma.

Authors:  Ali S Haider; Tarek Y El Ahmadieh; Maryam Haider; Kimmo J Hatanpaa; Marco C Pinho; Bruce E Mickey; Raymond Sawaya; Gregory N Fuller; Donald F Schomer; Maria Gule-Monroe
Journal:  Neuroradiology       Date:  2022-04-15       Impact factor: 2.995

3.  Clinical independent prognostic factors and overall survival prognostic nomogram for intracranial subependymoma: A SEER population-based analysis 2004-2016.

Authors:  Zibin Zhang; Xiaojun Pang; Yuyu Wei; Qingping Lv; Xuhong Jin; Huai Chen
Journal:  Front Oncol       Date:  2022-08-22       Impact factor: 5.738

  3 in total

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