Literature DB >> 2991279

The human vasopressin gene is linked to the oxytocin gene and is selectively expressed in a cultured lung cancer cell line.

E Sausville, D Carney, J Battey.   

Abstract

The human genes for prepro-arginine-vasopressin-neurophysin II (prepro-AVP-NPII) and prepro-oxytocin-neurophysin I (prepro-OT-NPI) were cloned from a human genomic library and the nucleotide sequence of both genes was determined. The two genes are similar in their intron-exon structure, linked together with 12 kilobases intervening, and transcribed from opposite DNA strands. A human small cell lung cancer cell line, H378, produces significant quantities of pre-pro-AVP-NPII mRNA using a transcription unit predicted from the genomic DNA sequence. Despite the proximity of the actively transcribed prepro-AVP-NPII gene, transcription of prepro-OT-NPI is not detected in this cell line.

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Year:  1985        PMID： 2991279

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  54 in total

1.  Mice transgenic for a vasopressin-SV40 hybrid oncogene develop tumors of the endocrine pancreas and the anterior pituitary. A possible model for human multiple endocrine neoplasia type 1.

Authors:  D Murphy; A Bishop; G Rindi; M N Murphy; G W Stamp; J Hanson; J M Polak; B Hogan
Journal:  Am J Pathol       Date:  1987-12       Impact factor: 4.307

2.  Carbetocin versus oxytocin in caesarean section with high risk of post-partum haemorrhage.

Authors:  Giovanni Larciprete; Carlotta Montagnoli; Mariagrazia Frigo; Valentina Panetta; Cristina Todde; Benedetta Zuppani; Chiara Centonze; Alessandro Bompiani; Ioannis Malandrenis; Alio Cirese; Herbert Valensise
Journal:  J Prenat Med       Date:  2013-01

Review 3.  Dual paraneoplastic syndromes: small cell lung carcinoma-related oncogenic osteomalacia, and syndrome of inappropriate antidiuretic hormone secretion: report of a case and review of the literature.

Authors:  Ekamol Tantisattamo; Roland C K Ng
Journal:  Hawaii Med J       Date:  2011-07

Review 4.  Structure-function relationships of the vasopressin prohormone domains.

Authors:  F M de Bree; J P Burbach
Journal:  Cell Mol Neurobiol       Date:  1998-04       Impact factor: 5.046

5.  Upstream stimulatory factor activates the vasopressin promoter via multiple motifs, including a non-canonical E-box.

Authors:  Judy M Coulson; Jodie L Edgson; Zoe V Marshall-Jones; Robert Mulgrew; John P Quinn; Penella J Woll
Journal:  Biochem J       Date:  2003-02-01       Impact factor: 3.857

Review 6.  The map of chromosome 20.

Authors:  N E Simpson
Journal:  J Med Genet       Date:  1988-12       Impact factor: 6.318

7.  Human small-cell lung cancers show amplification and expression of the N-myc gene.

Authors:  M M Nau; B J Brooks; D N Carney; A F Gazdar; J F Battey; E A Sausville; J D Minna
Journal:  Proc Natl Acad Sci U S A       Date:  1986-02       Impact factor: 11.205

8.  A single base substitution in the coding region for neurophysin II associated with familial central diabetes insipidus.

Authors:  M Ito; Y Mori; Y Oiso; H Saito
Journal:  J Clin Invest       Date:  1991-02       Impact factor: 14.808

9.  Two orphan receptors binding to a common site are involved in the regulation of the oxytocin gene in the bovine ovary.

Authors:  U Wehrenberg; R Ivell; M Jansen; S von Goedecke; N Walther
Journal:  Proc Natl Acad Sci U S A       Date:  1994-02-15       Impact factor: 11.205

10.  A murine model of autosomal dominant neurohypophyseal diabetes insipidus reveals progressive loss of vasopressin-producing neurons.

Authors:  Theron A Russell; Masafumi Ito; Mika Ito; Richard N Yu; Fred A Martinson; Jeffrey Weiss; J Larry Jameson
Journal:  J Clin Invest       Date:  2003-12       Impact factor: 14.808
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