Literature DB >> 2991142

Radiosynthesis of an opiate receptor binding radiotracer: [11C]carfentanil.

R F Dannals, H T Ravert, J J Frost, A A Wilson, H D Burns, H N Wagner.   

Abstract

Carfentanil, a potent opiate receptor agonist, was labeled with 11C for in vivo studies using positron emission tomography. This synthesis was completed in approximately 30 min using iodomethane as the 11C precursor. The synthesis, purification, characterization, and determination of specific activity are presented and discussed.

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Year:  1985        PMID: 2991142     DOI: 10.1016/0020-708x(85)90089-4

Source DB:  PubMed          Journal:  Int J Appl Radiat Isot        ISSN: 0020-708X


  27 in total

1.  mu-Opioid receptors and limbic responses to aversive emotional stimuli.

Authors:  Israel Liberzon; Jon Kar Zubieta; Lorraine M Fig; K Luan Phan; Robert A Koeppe; Stephan F Taylor
Journal:  Proc Natl Acad Sci U S A       Date:  2002-05-14       Impact factor: 11.205

2.  Alterations in endogenous opioid functional measures in chronic back pain.

Authors:  Ilkka K Martikainen; Marta Peciña; Tiffany M Love; Emily B Nuechterlein; Chelsea M Cummiford; Carmen R Green; Richard E Harris; Christian S Stohler; Jon-Kar Zubieta
Journal:  J Neurosci       Date:  2013-09-11       Impact factor: 6.167

Review 3.  Tracers for metabolic imaging of brain and heart. Radiochemistry and radiopharmacology.

Authors:  G Stöcklin
Journal:  Eur J Nucl Med       Date:  1992

4.  Pronociceptive and antinociceptive effects of estradiol through endogenous opioid neurotransmission in women.

Authors:  Yolanda R Smith; Christian S Stohler; Thomas E Nichols; Joshua A Bueller; Robert A Koeppe; Jon-Kar Zubieta
Journal:  J Neurosci       Date:  2006-05-24       Impact factor: 6.167

Review 5.  Non-invasive methods to study drug disposition: positron emission tomography. Detection and quantification of brain receptors in man.

Authors:  B Sadzot; G Franck
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1990 Apr-Jun       Impact factor: 2.441

6.  Evaluation of the agonist PET radioligand [¹¹C]GR103545 to image kappa opioid receptor in humans: kinetic model selection, test-retest reproducibility and receptor occupancy by the antagonist PF-04455242.

Authors:  Mika Naganawa; Leslie K Jacobsen; Ming-Qiang Zheng; Shu-Fei Lin; Anindita Banerjee; Wonkyung Byon; David Weinzimmer; Giampaolo Tomasi; Nabeel Nabulsi; Sarah Grimwood; Lori L Badura; Richard E Carson; Timothy J McCarthy; Yiyun Huang
Journal:  Neuroimage       Date:  2014-05-17       Impact factor: 6.556

Review 7.  Tactics for preclinical validation of receptor-binding radiotracers.

Authors:  Susan Z Lever; Kuo-Hsien Fan; John R Lever
Journal:  Nucl Med Biol       Date:  2016-09-03       Impact factor: 2.408

8.  Determination of in vivo Bmax and Kd for 11C-GR103545, an agonist PET tracer for κ-opioid receptors: a study in nonhuman primates.

Authors:  Giampaolo Tomasi; Nabeel Nabulsi; Ming-Qiang Zheng; David Weinzimmer; Jim Ropchan; Laura Blumberg; Clive Brown-Proctor; Yu-Shin Ding; Richard E Carson; Yiyun Huang
Journal:  J Nucl Med       Date:  2013-02-19       Impact factor: 10.057

Review 9.  Buprenorphine maintenance and mu-opioid receptor availability in the treatment of opioid use disorder: implications for clinical use and policy.

Authors:  Mark K Greenwald; Sandra D Comer; David A Fiellin
Journal:  Drug Alcohol Depend       Date:  2014-08-19       Impact factor: 4.492

10.  mu-opioid receptor-mediated antinociceptive responses differ in men and women.

Authors:  Jon-Kar Zubieta; Yolanda R Smith; Joshua A Bueller; Yanjun Xu; Michael R Kilbourn; Douglas M Jewett; Charles R Meyer; Robert A Koeppe; Christian S Stohler
Journal:  J Neurosci       Date:  2002-06-15       Impact factor: 6.167

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