Literature DB >> 2991114

Human lens gamma-crystallin sequences are located in the p12-qter region of chromosome 2.

J T den Dunnen, R J Jongbloed, A H Geurts van Kessel, J G Schoenmakers.   

Abstract

The human gamma-crystallin genes constitute a multigene family whose members are only expressed in the eye lens. The chromosomal location of these sequences has been determined by screening a panel of human/rodent hybrid cell lines containing overlapping subsets of human chromosomes for the presence of human gamma-crystallin sequences. By correlating these genomic hybridization data with the chromosomal constitution of the somatic cell hybrids, all human gamma-crystallin sequences could be assigned to chromosome 2. The use of human/hamster cell hybrids derived from human Burkitt lymphoma cells carrying a reciprocal translocation between human chromosomes 2 and 8, allowed a further localization of the sequences to the region 2p12-qter.

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Year:  1985        PMID： 2991114     DOI： 10.1007/bf00273445

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  15 in total

1.  Expression of recessive alleles by chromosomal mechanisms in retinoblastoma.

Authors:  W K Cavenee; T P Dryja; R A Phillips; W F Benedict; R Godbout; B L Gallie; A L Murphree; L C Strong; R L White
Journal:  Nature       Date:  1983 Oct 27-Nov 2       Impact factor: 49.962

Review 2.  Report of the Committee on the Genetic Constitution of Chromosomes 2, 3, 4, and 5.

Authors:  D Bootsma; K K Kidd
Journal:  Cytogenet Cell Genet       Date:  1984

3.  The making of strand-specific M13 probes.

Authors:  N Hu; J Messing
Journal:  Gene       Date:  1982-03       Impact factor: 3.688

4.  Eye-lens proteins: the three-dimensional structure of beta-crystallin predicted from monomeric gamma-crystallin.

Authors:  G Wistow; C Slingsby; T Blundell; H Driessen; W De Jong; H Bloemendal
Journal:  FEBS Lett       Date:  1981-10-12       Impact factor: 4.124

5.  Primary structure of the bovine beta-crystallin Bp chain. Internal duplication and homology with gamma-crystallin.

Authors:  H P Driessen; P Herbrink; H Bloemendal; W W de Jong
Journal:  Eur J Biochem       Date:  1981-12

Review 6.  Lens proteins.

Authors:  H Bloemendal
Journal:  CRC Crit Rev Biochem       Date:  1982

7.  Expression of human myeloid-associated surface antigens in human-mouse myeloid cell hybrids.

Authors:  A H Geurts van Kessel; P A Tetteroo; A E von dem Borne; A Hagemeijer; D Bootsma
Journal:  Proc Natl Acad Sci U S A       Date:  1983-06       Impact factor: 11.205

8.  Deficiency of functional messenger RNA for a developmentally regulated beta-crystallin polypeptide in a hereditary cataract.

Authors:  D Carper
Journal:  Science       Date:  1982-07-30       Impact factor: 47.728

9.  Characterization of the Philadelphia chromosome by gene mapping.

Authors:  A H Geurts van Kessel; H ten Brinke; W A Boere; W C den Boer; P G de Groot; A Hagemeijer; P Meera Khan; P L Pearson
Journal:  Cytogenet Cell Genet       Date:  1981

10.  Evolution and diversity of the crystallins. Nucleotide sequence of a beta-crystallin mRNA from the mouse lens.

Authors:  G Inana; T Shinohara; J V Maizel; J Piatigorsky
Journal:  J Biol Chem       Date:  1982-08-10       Impact factor: 5.157
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  11 in total

Review 1.  A superfamily in the mammalian eye lens: the beta/gamma-crystallins.

Authors:  G L van Rens; W W de Jong; H Bloemendal
Journal:  Mol Biol Rep       Date:  1992-02       Impact factor: 2.316

2.  Assignment of the gene(s) involved in the expression of the proliferation-related Ki-67 antigen to human chromosome 10.

Authors:  D M Schonk; H J Kuijpers; E van Drunen; C H van Dalen; A H Geurts van Kessel; R Verheijen; F C Ramaekers
Journal:  Hum Genet       Date:  1989-10       Impact factor: 4.132

3.  The eye lens crystallins: ambiguity as evolutionary strategy.

Authors:  W W de Jong; W Hendriks
Journal:  J Mol Evol       Date:  1986       Impact factor: 2.395

4.  Assignment of the human gamma-crystallin gene cluster (CRYG) to the long arm of chromosome 2, region q33-36.

Authors:  Y Shiloh; T Donlon; G Bruns; M L Breitman; L C Tsui
Journal:  Hum Genet       Date:  1986-05       Impact factor: 4.132

5.  Confirmation of assignment of the human alpha 1-crystallin gene (CRYA1) to chromosome 21 with regional localization to q22.3.

Authors:  J W Hawkins; M L Van Keuren; J Piatigorsky; M L Law; D Patterson; F T Kao
Journal:  Hum Genet       Date:  1987-08       Impact factor: 4.132

6.  Gamma-crystallins of the human eye lens: expression analysis of five members of the gene family.

Authors:  S O Meakin; R P Du; L C Tsui; M L Breitman
Journal:  Mol Cell Biol       Date:  1987-08       Impact factor: 4.272

7.  The gamma-crystallin gene families: sequence and evolutionary patterns.

Authors:  H J Aarts; J T den Dunnen; J Leunissen; N H Lubsen; J G Schoenmakers
Journal:  J Mol Evol       Date:  1988       Impact factor: 2.395

8.  Relationship between proteins encoded by three human gamma-crystallin genes and distinct polypeptides in the eye lens.

Authors:  P Russell; S O Meakin; T C Hohman; L C Tsui; M L Breitman
Journal:  Mol Cell Biol       Date:  1987-09       Impact factor: 4.272

9.  A locus for a human hereditary cataract is closely linked to the gamma-crystallin gene family.

Authors:  N H Lubsen; J H Renwick; L C Tsui; M L Breitman; J G Schoenmakers
Journal:  Proc Natl Acad Sci U S A       Date:  1987-01       Impact factor: 11.205

10.  Human lens gamma-crystallins: isolation, identification, and characterization of the expressed gene products.

Authors:  R J Siezen; J A Thomson; E D Kaplan; G B Benedek
Journal:  Proc Natl Acad Sci U S A       Date:  1987-09       Impact factor: 11.205
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