Literature DB >> 2991002

The amiloride sensitive Na+/H+ antiport in guinea pig pancreatic acini. Characterization and stimulation by caerulein.

M Dufresne, M J Bastie, N Vaysse, Y Creach, E Hollande, A Ribet.   

Abstract

Amiloride and analogs decrease the initial rate of 22Na+ uptake by dispersed acini from guinea pig pancreas in a dose-dependent manner. The initial rate of amiloride-sensitive 22Na+ uptake depends on external Na+ and H+ concentrations and on internal pH. These results provide evidence for the existence of a Na+/H+ antiport in pancreatic acinar cells. Caerulein, a cholecystokinin analog, stimulates the activity of the Na+/H+ antiport.

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Year:  1985        PMID: 2991002     DOI: 10.1016/0014-5793(85)81227-8

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  7 in total

Review 1.  Mechanisms of regulation of the Na+/H+ exchanger.

Authors:  S Grinstein; A Rothstein
Journal:  J Membr Biol       Date:  1986       Impact factor: 1.843

2.  Creatine phosphate as energy source in the cerulein-stimulated rat pancreas study by 31P nuclear magnetic resonance.

Authors:  S Aired; Y Creach; C Palevody; J Esclassan; E Hollande
Journal:  Int J Pancreatol       Date:  1991-09

3.  Acetylcholine-induced Na+ influx in the mouse lacrimal gland acinar cells: demonstration of multiple Na+ transport mechanisms by intracellular Na+ activity measurements.

Authors:  Y Saito; T Ozawa; A Nishiyama
Journal:  J Membr Biol       Date:  1987       Impact factor: 1.843

4.  CCK-related peptides stimulation of the Na+/H+ antiport in pancreatic acinar cells leads to cytoplasmic alkalinisation.

Authors:  M J Bastie; M Dufresne; M Delvaux; N Vaysse; A Ribet
Journal:  Gut       Date:  1987       Impact factor: 23.059

5.  Effects of intra- and extracellular H+ and Na+ concentrations on Na(+)-H+ antiport activity in the lacrimal gland acinar cells.

Authors:  Y Saito; T Ozawa; A Nishiyama
Journal:  Pflugers Arch       Date:  1990-12       Impact factor: 3.657

6.  Na+, K+, and Cl- transport in resting pancreatic acinar cells.

Authors:  H Zhao; S Muallem
Journal:  J Gen Physiol       Date:  1995-12       Impact factor: 4.086

7.  Agonist-specific regulation of [Na+]i in pancreatic acinar cells.

Authors:  H Zhao; S Muallem
Journal:  J Gen Physiol       Date:  1995-12       Impact factor: 4.086

  7 in total

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