Nils G Margraf1, Robin Wolke1, Oliver Granert1, Alfredo Berardelli2, Bastian R Bloem3, Ruth Djaldetti4, Alberto J Espay5, Alfonso Fasano6, Yoshihiko Furusawa7, Nir Giladi8, Mark Hallett9, Joseph Jankovic10, Miho Murata7, Michele Tinazzi11, Jens Volkmann12, Daniela Berg1, Günther Deuschl13. 1. Department of Neurology, UKSH, Christian-Albrechts University Kiel, Germany. 2. Department of Human Neuroscience, Sapienza, University of Rome and IRCCS NEUROMED, Pozzilli, Italy. 3. Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Nijmegen, The Netherlands. 4. Department of Neurology, Movement Disorder Unit, Rabin Medical Center, Petach Tiqva and the Sackler Faculty of Medicine, Ramat Aviv, Tel Aviv, Israel. 5. Gardner Family Center for Parkinson's Disease and Movement Disorders, Department of Neurology, University of Cincinnati, Cincinnati, OH, USA. 6. Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Toronto, Ontario, Canada; Division of Neurology, University of Toronto, Toronto, Ontario, Canada; Krembil Research Institute, Toronto, Ontario, Canada. 7. National Center of Neurology & Psychiatry, Tokyo, Japan. 8. Neurological Institute, Tel-Aviv Medical Center, Sackler School of Medicine, Sagol School of Neurosciences, Tel-Aviv University, Tel-Aviv, Israel. 9. Human Motor Control Section, NINDS, NIH, Bethesda, MD, USA. 10. Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, TX, USA. 11. Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy. 12. Department of Neurology, Universitätsklinikum Würzburg, Germany. 13. Department of Neurology, UKSH, Christian-Albrechts University Kiel, Germany. Electronic address: g.deuschl@neurologie.uni-kiel.de.
Abstract
INTRODUCTION: Camptocormia is characterized by a pathological forward flexion of the trunk, which is reversible when lying and worsened by standing and walking. So far there is no consensus on how to measure the angle of flexion, and studies therefore give differing results. Harmonization is needed for both research and clinical practice. Orthopedic measures are not useful for this purpose. METHODS: Two expert raters independently analyzed the photographs of 39 Parkinson patients with camptocormia while standing. They used four different methods to determine the camptocormia angle. The results were compared statistically. An international Consensus Group reviewed the results and drafted recommendations. RESULTS: The four methods yielded camptocormia angles that differed by up to 50% in the same patient. Inter-rater reliability and test-retest reliability also differed, but were satisfactory to excellent. CONCLUSION: This Consensus Group concluded that two of the methods qualified as reliable measures of the trunk angles in standing patients based on their clinimetric properties. They propose that the 'total camptocomia angle' be the angle between the line from the lateral malleolus to the L5 spinous process and the line between the L5 spinous process and the spinous process of C7. They also propose that the 'upper camptocormia angle' be the angle of the lines between the vertebral fulcrum to the spinous processes of L5 and C7, respectively. An app is provided on the web for these measurements (http://www.neurologie.uni-kiel.de/de/axial-posturale-stoerungen/camptoapp).
INTRODUCTION: Camptocormia is characterized by a pathological forward flexion of the trunk, which is reversible when lying and worsened by standing and walking. So far there is no consensus on how to measure the angle of flexion, and studies therefore give differing results. Harmonization is needed for both research and clinical practice. Orthopedic measures are not useful for this purpose. METHODS: Two expert raters independently analyzed the photographs of 39 Parkinsonpatients with camptocormia while standing. They used four different methods to determine the camptocormia angle. The results were compared statistically. An international Consensus Group reviewed the results and drafted recommendations. RESULTS: The four methods yielded camptocormia angles that differed by up to 50% in the same patient. Inter-rater reliability and test-retest reliability also differed, but were satisfactory to excellent. CONCLUSION: This Consensus Group concluded that two of the methods qualified as reliable measures of the trunk angles in standing patients based on their clinimetric properties. They propose that the 'total camptocomia angle' be the angle between the line from the lateral malleolus to the L5 spinous process and the line between the L5 spinous process and the spinous process of C7. They also propose that the 'upper camptocormia angle' be the angle of the lines between the vertebral fulcrum to the spinous processes of L5 and C7, respectively. An app is provided on the web for these measurements (http://www.neurologie.uni-kiel.de/de/axial-posturale-stoerungen/camptoapp).
Authors: Urban M Fietzek; Frauke E Schroeteler; Lisa Hahn; Kerstin Ziegler; Andres O Ceballos-Baumann Journal: J Neural Transm (Vienna) Date: 2018-08-07 Impact factor: 3.575
Authors: Christian Schlenstedt; Olga Gavriliuc; Kathrin Boße; Robin Wolke; Oliver Granert; Günther Deuschl; Nils G Margraf Journal: Front Neurol Date: 2019-12-03 Impact factor: 4.003
Authors: Christian Geroin; Carlo Alberto Artusi; Marialuisa Gandolfi; Elisabetta Zanolin; Roberto Ceravolo; Marianna Capecci; Elisa Andrenelli; Maria Gabriella Ceravolo; Laura Bonanni; Marco Onofrj; Roberta Telese; Giulia Bellavita; Mauro Catalan; Paolo Manganotti; Sonia Mazzucchi; Sara Giannoni; Laura Vacca; Fabrizio Stocchi; Miriam Casali; Cristian Falup-Pecurariu; Maurizio Zibetti; Alfonso Fasano; Leonardo Lopiano; Michele Tinazzi Journal: Front Neurol Date: 2020-03-31 Impact factor: 4.003