Literature DB >> 2990449

Effect of the chaotropic anions thiocyanate and perchlorate on the entry of ricin into Vero cells.

K Sandvig, S Olsnes.   

Abstract

The effect of different anions on the sensitivity of Vero cells to ricin was investigated. The cells were equally sensitive to ricin when NaCl was replaced by NaBr, NaI, Na2SO4 or with iso-osmotic concentrations of mannitol. In contrast, NaSCN and NaClO4 strongly protected against ricin at pH 7.2, but not at pH 7.6. The possibility that the protective effect is due to the ability of chaotropic anions to decrease the pH close to the membrane is discussed.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 2990449      PMCID： PMC1145012          DOI： 10.1042/bj2280521

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  8 in total

1.  Chaotropic anions and the surface potential of bilayer membranes.

Authors:  S McLaughlin; A Bruder; S Chen; C Moser
Journal:  Biochim Biophys Acta       Date:  1975-06-25

2.  Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells.

Authors:  K Sandvig; S Olsnes
Journal:  Exp Cell Res       Date:  1979-06       Impact factor: 3.905

3.  Isolation and properties of abrin: a toxic protein inhibiting protein synthesis. Evidence for different biological functions of its two constituent-peptide chains.

Authors:  S Olsnes; A Pihl
Journal:  Eur J Biochem       Date:  1973-05

4.  Different biological properties of the two constituent peptide chains of ricin, a toxic protein inhibiting protein synthesis.

Authors:  S Olsnes; A Pihl
Journal:  Biochemistry       Date:  1973-07-31       Impact factor: 3.162

5.  Interfacial pH at electrically charged lipid monolayers investigated by the lipoid pH-indicator method.

Authors:  P Fromherz; B Masters
Journal:  Biochim Biophys Acta       Date:  1974-08-09

6.  Anion requirement and effect of anion transport inhibitors on the response of vero cells to diphtheria toxin and modeccin.

Authors:  K Sandvig; S Olsnes
Journal:  J Cell Physiol       Date:  1984-04       Impact factor: 6.384

7.  Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium.

Authors:  K Sandvig; S Olsnes
Journal:  J Biol Chem       Date:  1982-07-10       Impact factor: 5.157

8.  Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril.

Authors:  P J Fraker; J C Speck
Journal:  Biochem Biophys Res Commun       Date:  1978-02-28       Impact factor: 3.575
  8 in total
  1 in total

1.  Ion modulation of membrane permeability: effect of cations on intact cells and on cells and phospholipid bilayers treated with pore-forming agents.

Authors:  C L Bashford; G M Alder; J M Graham; G Menestrina; C A Pasternak
Journal:  J Membr Biol       Date:  1988-07       Impact factor: 1.843
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.