Débora Alves Guariglia1, Rafael Evangelista Pedro2, Rafael Deminice3, Flávia Troncon Rosa4, Sidney Barnabé Peres5, Solange Marta Franzói De Moraes6. 1. Estácio de Sá de Ourinhos University, Ourinhos, Brazil. Electronic address: debora.guariglia@gmail.com. 2. Adipose Tissue Study Group - Department of Physiological Sciences, State University of Maringá, Maringá, Brazil. Electronic address: rafaelevangelista13@hotmail.com. 3. Department of Physical Education, State University of Londrina, Londrina, Brazil. Electronic address: rdeminice@uel.br. 4. Department of Nutrition, Filadelfia University, Londrina, Brazil. Electronic address: flaviatrosa@yahoo.com.br. 5. Department of Physiological Sciences, State University of Maringá, Maringá, Brazil. Electronic address: sbperes@uem.br. 6. Department of Physiological Sciences, State University of Maringá, Maringá, Brazil. Electronic address: smfmoraes@uem.br.
Abstract
PURPOSE: The aim of this study was to conduct a randomized clinical trial to assess the effects of 16 weeks of combined training on body composition, lipid profile, adiponectin, C-reactive protein (CRP), and leptin levels in people living with HIV/AIDS (PLWHA). METHODS:Fifty-eight HIV-infected individuals were randomized into a training group (T) or a control group (C). Combined training consisted of aerobic and resistance exercises performed at the same training session, applied at a frequency of three times a week for a total of 16 weeks. Waist circumference, body mass, body fat percentage (%fat), fat mass, lipid profile, adiponectin, CRP, and leptin levels were measured pre- and post-training in both groups. RESULTS: Sixteen weeks of combined training decreased (P < 0.05) body fat in different body segments in PLWHA. Lipodystrophic PLWHA experienced greater reduction in body fat in the android region than non-lipodystrophic PLWHA after combined training. Lipid profile and circulating levels of adiponectin, leptin, and CRP remained unchanged. CONCLUSIONS: Sixteen weeks of combined training was effective to reduce body fat in different body segments, without altering plasma lipid and cytokine levels.
RCT Entities:
PURPOSE: The aim of this study was to conduct a randomized clinical trial to assess the effects of 16 weeks of combined training on body composition, lipid profile, adiponectin, C-reactive protein (CRP), and leptin levels in people living with HIV/AIDS (PLWHA). METHODS: Fifty-eight HIV-infected individuals were randomized into a training group (T) or a control group (C). Combined training consisted of aerobic and resistance exercises performed at the same training session, applied at a frequency of three times a week for a total of 16 weeks. Waist circumference, body mass, body fat percentage (%fat), fat mass, lipid profile, adiponectin, CRP, and leptin levels were measured pre- and post-training in both groups. RESULTS: Sixteen weeks of combined training decreased (P < 0.05) body fat in different body segments in PLWHA. Lipodystrophic PLWHA experienced greater reduction in body fat in the android region than non-lipodystrophic PLWHA after combined training. Lipid profile and circulating levels of adiponectin, leptin, and CRP remained unchanged. CONCLUSIONS: Sixteen weeks of combined training was effective to reduce body fat in different body segments, without altering plasma lipid and cytokine levels.
Authors: Catherine M Jankowski; Samantha Mawhinney; Melissa P Wilson; Thomas B Campbell; Wendy M Kohrt; Robert S Schwartz; Todd T Brown; Kristine M Erlandson Journal: J Acquir Immune Defic Syndr Date: 2020-11-01 Impact factor: 3.771