Literature DB >> 29903575

CXCL4 and CXCL4L1 in cancer.

Pieter Ruytinx1, Paul Proost1, Sofie Struyf2.   

Abstract

Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes. Here we review the role of CXCL4 and CXCL4L1 in cancer, the use of both chemokines as cancer biomarkers and discuss some possible therapeutic opportunities.
Copyright © 2018. Published by Elsevier Ltd.

Entities:  

Keywords:  CXCL4; CXCL4L1; Chemokines; Tumor

Mesh：

Substances：

Year:  2018        PMID： 29903575     DOI： 10.1016/j.cyto.2018.02.022

Source DB:  PubMed          Journal:  Cytokine        ISSN： 1043-4666            Impact factor:   3.861


  10 in total

1.  CXCL4L1 May Help Differentiate Benign from Malignant Pulmonary Lesions and Predicts Prognosis of Patients with Lung Cancer.

Authors:  Lei Zhang; Guangping Li; Hongxin Zhang; Huaqun Liu; Songlin Li; Yanan Wang; Huisheng Qi
Journal:  Cancer Manag Res       Date:  2022-06-07       Impact factor: 3.602

2.  Genome-Wide Profiling of Alternative Splicing Signature Reveals Prognostic Predictor for Esophageal Carcinoma.

Authors:  Jian-Rong Sun; Chen-Fan Kong; Yan-Ni Lou; Ran Yu; Xiang-Ke Qu; Li-Qun Jia
Journal:  Front Genet       Date:  2020-07-22       Impact factor: 4.599

Review 3.  Chemokine Heterocomplexes and Cancer: A Novel Chapter to Be Written in Tumor Immunity.

Authors:  Gianluca D'Agostino; Valentina Cecchinato; Mariagrazia Uguccioni
Journal:  Front Immunol       Date:  2018-09-25       Impact factor: 7.561

4.  PF4V1, an miRNA-875-3p target, suppresses cell proliferation, migration, and invasion in prostate cancer and serves as a potential prognostic biomarker.

Authors:  Dongyang Li; Xuanyu Hao; Yudi Dong; Mo Zhang; Yongsheng Song
Journal:  Cancer Manag Res       Date:  2019-03-21       Impact factor: 3.989

Review 5.  Mechanisms of Immunosuppression in Colorectal Cancer.

Authors:  Yang Zhang; Ashwani Rajput; Ning Jin; Jing Wang
Journal:  Cancers (Basel)       Date:  2020-12-20       Impact factor: 6.639

6.  Galectin-1 and platelet factor 4 (CXCL4) induce complementary platelet responses in vitro.

Authors:  Annemiek Dickhout; Bibian M E Tullemans; Johan W M Heemskerk; Victor L J L Thijssen; Marijke J E Kuijpers; Rory R Koenen
Journal:  PLoS One       Date:  2021-01-07       Impact factor: 3.240

7.  Association of mammographic density with blood DNA methylation.

Authors:  Rachel M Lucia; Wei-Lin Huang; Andrea Alvarez; Irene Masunaka; Argyrios Ziogas; Deborah Goodman; Andrew O Odegaard; Trina M Norden-Krichmar; Hannah Lui Park
Journal:  Epigenetics       Date:  2021-06-11       Impact factor: 4.861

8.  Clinical Assay for the Early Detection of Colorectal Cancer Using Mass Spectrometric Wheat Germ Agglutinin Multiple Reaction Monitoring.

Authors:  I-Jung Tsai; Emily Chia-Yu Su; I-Lin Tsai; Ching-Yu Lin
Journal:  Cancers (Basel)       Date:  2021-05-02       Impact factor: 6.639

9.  Circular RNA hsa_circ_0069117 suppresses proliferation and migration of osteosarcoma cells lines via miR-875-3p/PF4V1 axis.

Authors:  Ziyan Zhang; Lin Zhou; Shicheng Zhou; Xin Li
Journal:  J Orthop Surg Res       Date:  2022-01-21       Impact factor: 2.359

10.  Identification of six hub genes and analysis of their correlation with drug sensitivity in acute myeloid leukemia through bioinformatics.

Authors:  Daxia Cai; Jiajian Liang; Xing-Dong Cai; Ying Yang; Gexiu Liu; Fenling Zhou; Dongmei He
Journal:  Transl Cancer Res       Date:  2021-01       Impact factor: 1.241
  10 in total

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