Literature DB >> 29900564

Power outages and refrigerated medicines: The need for better guidelines, awareness and planning.

S Kosari1, E J Walker1, C Anderson1, G M Peterson2, M Naunton1, E Castillo Martinez1, S Garg3, J Thomas1.   

Abstract

WHAT IS KNOWN AND
OBJECTIVE: Vaccines and other pharmaceuticals are essential medical supplies that require continuous storage at specific temperatures to maintain viability. Power outages can lead to a break in the cold chain, resulting in the degradation of essential medicines. COMMENT: After a power outage, the stability of vaccines and other medicines can be difficult to ascertain. Many public health guidelines therefore recommend discarding potentially compromised pharmaceuticals unless the cold chain can be guaranteed-a costly endeavour. There are government guidelines aimed at minimizing exposure to high temperatures in the event of a power outage; however, the usefulness of these guidelines is uncertain. WHAT IS NEW AND
CONCLUSION: The actual cost of vaccine and pharmaceutical loss due to a break in the cold chain is poorly studied and requires further research. Additional recommendations regarding the stability of specific medicines would also be a valuable resource.
© 2018 John Wiley & Sons Ltd.

Keywords:  cold-chain breach; medication stability; medication wastage; power outage; refrigerated medicines

Mesh:

Substances:

Year:  2018        PMID: 29900564     DOI: 10.1111/jcpt.12716

Source DB:  PubMed          Journal:  J Clin Pharm Ther        ISSN: 0269-4727            Impact factor:   2.512


  2 in total

1.  Application of Failure Mode, Effects, and Criticality Analysis to the Medication-Use Process for Temperature-Sensitive Drugs in a University Hospital.

Authors:  Hana Sakly; Ines Chakroun; Khouloud Ben Jeddou
Journal:  Can J Hosp Pharm       Date:  2022-07-04

Review 2.  [Knowledge gained from a 31-h power outage in Berlin Köpenick-medical problems and challenges].

Authors:  Florian Breuer; Paul Brettschneider; Per Kleist; Stefan Poloczek; Christopher Pommerenke; Janosch Dahmen
Journal:  Anaesthesist       Date:  2021-02-23       Impact factor: 1.041

  2 in total

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