Literature DB >> 2989967

Increase in plasma ACTH after dopaminergic stimulation in rats.

D Jezová, J Jurcovicová, M Vigas, K Murgas, F Labrie.   

Abstract

The effects of a dopaminergic agonist, apomorphine, and a dopaminergic antagonist, haloperidol, on plasma ACTH, and corticosterone levels were evaluated in adult male rats. Subcutaneous administration of apomorphine in the dose range of 50-500 micrograms X kg-1 significantly increased plasma corticosterone levels. Acute treatment with apomorphine (250 micrograms X kg-1) resulted in an elevation of plasma ACTH concentration, peak values being reached 15 min after the injection. The apomorphine-induced rise in plasma ACTH levels was completely inhibited by pretreatment with haloperidol (1 mg X kg-1). A stimulatory role for dopamine receptors in the control of pituitary ACTH release in the rat is suggested.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 2989967     DOI： 10.1007/bf00428414

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  6 in total

Review 1.  Role of brain monoamines and histamine in regulation of anterior pituitary secretion.

Authors:  R I Weiner; W F Ganong
Journal:  Physiol Rev       Date:  1978-10       Impact factor: 37.312

Review 2.  The role of serotonin and dopamine in hypothalamic-pituitary function.

Authors:  G A Smythe
Journal:  Clin Endocrinol (Oxf)       Date:  1977-10       Impact factor: 3.478

3.  Some studies of the protein-binding of steroids and their application to the routine micro and ultramicro measurement of various steroids in body fluids by competitive protein-binding radioassay.

Authors:  B E Murphy
Journal:  J Clin Endocrinol Metab       Date:  1967-07       Impact factor: 5.958

4.  Elevation of serum corticosterone concentrations in rats by pergolide and other dopamine agonists.

Authors:  R W Fuller; H D Snoddy
Journal:  Endocrinology       Date:  1981-10       Impact factor: 4.736

5.  The role of biogenic amines in the regulation of growth hormone and corticotropin secretion in the trained conscious dog.

Authors:  F J Holland; G E Richards; S L Kaplan; W F Ganong; M M Grumbach
Journal:  Endocrinology       Date:  1978-05       Impact factor: 4.736

6.  Elevation of serum corticosterone in rats by dopamine agonists related in structure to pergolide.

Authors:  R W Fuller; H D Snoddy; N R Mason; J A Clemens; K G Bemis
Journal:  Neuroendocrinology       Date:  1983       Impact factor: 4.914
  6 in total
  6 in total

1.  Revealing the Neuroendocrine Response After Remoxipride Treatment Using Multi-Biomarker Discovery and Quantifying It by PK/PD Modeling.

Authors:  Willem J van den Brink; Yin C Wong; Berfin Gülave; Piet H van der Graaf; Elizatbeth C M de Lange
Journal:  AAPS J       Date:  2016-10-26       Impact factor: 4.009

2.  Dopamine D1 and D2 dopamine receptors regulate immobilization stress-induced activation of the hypothalamus-pituitary-adrenal axis.

Authors:  Xavier Belda; Antonio Armario
Journal:  Psychopharmacology (Berl)       Date:  2009-07-21       Impact factor: 4.530

3.  Repeated amphetamine administration in rats revealed consistency across days and a complete dissociation between locomotor and hypothalamic-pituitary-adrenal axis effects of the drug.

Authors:  Humberto Gagliano; Raül Andero; Antonio Armario; Roser Nadal
Journal:  Psychopharmacology (Berl)       Date:  2009-10-07       Impact factor: 4.530

4.  Bromocriptine-induced hyperglycemia in nonobese diabetic mice: kinetics and mechanisms of action.

Authors:  Sylvie Durant; Josiane Coulaud; Francoise Homo-Delarche
Journal:  Rev Diabet Stud       Date:  2007-11-10

Review 5.  Adaptive Modifications of Maternal Hypothalamic-Pituitary-Adrenal Axis Activity during Lactation and Salsolinol as a New Player in this Phenomenon.

Authors:  Malgorzata Hasiec; Tomasz Misztal
Journal:  Int J Endocrinol       Date:  2018-04-10       Impact factor: 3.257

Review 6.  Psychotropic Drug Effects on Steroid Stress Hormone Release and Possible Mechanisms Involved.

Authors:  Zuzana Romanova; Natasa Hlavacova; Daniela Jezova
Journal:  Int J Mol Sci       Date:  2022-01-14       Impact factor: 5.923
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.