Celia Rodd1, Allison Feely2, Allison Dart3, Atul Sharma4, Jon McGavock5. 1. Department of Pediatrics and Child Health, Section of Pediatric Endocrinology, Winnipeg, Manitoba, R3E 0Z2, Canada. crodd@hsc.mb.ca. 2. University of Manitoba, Winnipeg, Manitoba, R3T 2M8, Canada. 3. Department of Pediatrics and Child Health, Section of Pediatric Nephrology, Winnipeg, Manitoba, R3E 0Z2, Canada. 4. Department of Pediatrics and Child Health, Winnipeg, Manitoba, R3A 1S1, Canada. 5. Children's Hospital Research Institute of Manitoba, 511 - 715 McDermot Ave, Winnipeg, Manitoba, R3E 3P4, Canada.
Abstract
OBJECTIVES: To describe rates of prediabetes among youth in Canada and the associated social and biological characteristics. METHODS: We analyzed the cross-sectional data from the first (2007-2009) and second (2009-2011) cycles of the Canadian Health Measures Survey (CHMS) for youth aged 6-19 years. Prediabetes was defined using the glycated hemoglobin (A1C) guidelines set out by the American Diabetes Association (ADA) and the Canadian Diabetes Association (CDA) of A1C ranges 5.7-6.4% (38.8-46.4 mmol/mol) and 6.0-6.4% (42.1-46.4 mmol/mol), respectively. RESULTS: An elevated A1C was observed in 22.8% of our sample (n = 3449) based on the ADA definition and 5.2% of youth using the CDA definition. Independent predictors in a fully adjusted model for prediabetes were non-White (odds ratio (OR) 2.62: 95% Confidence intervals 2.05-3.35), obese (OR 1.53: 1.19-1.96), less physically active youth (0.97: 0.95-0.99), and parents with high school education or less (1.34: 1.02-1.74). Moreover, significant regional variations were noted with higher rates for all regions except Ontario. CONCLUSION: Prediabetes is relatively common in Canada and associated with common biologic and socioeconomic factors. Importantly, regular physical activity was significantly associated with reduced odds of prediabetes. Targeted screening and continued emphasis on physical activity may help curb the increasing rates of prediabetes.
OBJECTIVES: To describe rates of prediabetes among youth in Canada and the associated social and biological characteristics. METHODS: We analyzed the cross-sectional data from the first (2007-2009) and second (2009-2011) cycles of the Canadian Health Measures Survey (CHMS) for youth aged 6-19 years. Prediabetes was defined using the glycated hemoglobin (A1C) guidelines set out by the American Diabetes Association (ADA) and the Canadian Diabetes Association (CDA) of A1C ranges 5.7-6.4% (38.8-46.4 mmol/mol) and 6.0-6.4% (42.1-46.4 mmol/mol), respectively. RESULTS: An elevated A1C was observed in 22.8% of our sample (n = 3449) based on the ADA definition and 5.2% of youth using the CDA definition. Independent predictors in a fully adjusted model for prediabetes were non-White (odds ratio (OR) 2.62: 95% Confidence intervals 2.05-3.35), obese (OR 1.53: 1.19-1.96), less physically active youth (0.97: 0.95-0.99), and parents with high school education or less (1.34: 1.02-1.74). Moreover, significant regional variations were noted with higher rates for all regions except Ontario. CONCLUSION:Prediabetes is relatively common in Canada and associated with common biologic and socioeconomic factors. Importantly, regular physical activity was significantly associated with reduced odds of prediabetes. Targeted screening and continued emphasis on physical activity may help curb the increasing rates of prediabetes.
Authors: Jesse A Goodrich; Tanya L Alderete; Brittney O Baumert; Kiros Berhane; Zhanghua Chen; Frank D Gilliland; Michael I Goran; Xin Hu; Dean P Jones; Katerina Margetaki; Sarah Rock; Nikos Stratakis; Damaskini Valvi; Douglas I Walker; David V Conti; Leda Chatzi Journal: Environ Health Perspect Date: 2021-09-01 Impact factor: 9.031