| Literature DB >> 29898299 |
Diogo Rijo1, Sara Simões Costa1, João Pedro Monteiro1, Marco Oliveira1, Ricardo Ferraz1, Fátima Neves1, Luís Vouga1, Miguel Guerra2.
Abstract
Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS) are two autoimmune diseases that may have serious cardiovascular manifestations, especially when associated. We report the clinical case of a young female, in the puerperium, with SLE in acute phase, who developed a sudden heart failure due to rupture of the papillary muscle. She underwent emergent cardiac surgery, with replacement of the mitral valve by a biological prosthesis. The postoperative course had no major intercurrences. Catastrophic SAF was concluded as a final diagnosis, due to the presence of anti-phospholipid antibody, to the attainment of multiple organs by thromboembolic phenomena, with histological documentation of micro-thrombi in cardiac tissue. This condition has a mortality rate of about 50%, despite treatment.Entities:
Mesh:
Year: 2017 PMID: 29898299
Source DB: PubMed Journal: Rev Port Cir Cardiotorac Vasc ISSN: 0873-7215